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Cat. No. Product Name Field of Application Chemical Structure
DC5105 Favipiravir (T-705) Featured
T 705(Favipiravir) is a RNA-directed RNA polymerase NS5B inhibitor.T 705(Favipiravir) is useful for Antiviral agents.
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DC8852 SW-044248 Featured
SW-044248 is a Novel Inhibitor of Topoisomerase I Is Selectively Toxic for a Subset of Non-Small Cell Lung Cancer Cell Lines.
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DC8267 SW033291 Featured
SW033291 is a potent inhibitor of 15-PGDH enzyme with IC50 value of 1.5 nM and dissociation constant Ki app value of 0.1 nM.
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DC3146 Sunitinib malate Featured
Sunitinib Malate (Sutent, SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.
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DC10664 Substance P free acid Featured
Substance P free acid is a Sensory neuropeptide and inflammatory mediator. Exerts excitatory effects on central and peripheral neurons, constricts bronchioles and is involved in pain transmission.
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DC6906 Aprepitant (MK-0869, L-754030) Featured
Substance P antagonists (SPA).
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DC9950 SU5614 Featured
SU5614 is a potent and selective FLT3 inhibitor.
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DC7508 SU 5402 Featured
SU5402(SU-5402; SU5402) is potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor. (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively).
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DC1093 SU11274 (PKI-SU11274) Featured
SU11274 is a selective Met inhibitor with IC50 of 10 nM.
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DC10519 SU 5214 Featured
SU 5214 is a modulator of tyrosine kinase signal transduction.
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DC9961 STO-609 Featured
STO-609 is a selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki values are 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively); competes for the ATP-binding site.
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DC10201 STK16-IN-1 Featured
STK16-IN-1 is a STK16 kinase inhibitor with an IC50 of 295 nM.
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DC10959 STING inhibitor C-178 Featured
STING inhibitor C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING; covalently binds to Cys91, directly targets mouse STING (mmSTING) but not human STING (hsSTING).
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DC10960 STING inhibitor C-176 Featured
STING inhibitor C-178 is a covalent, in vivo-active, small-molecule inhibitor of STING
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DC8413 STF-083010 Featured
STF-083010 is a specific IRE1α endonuclease inhibitor.
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DCAPI1051 Arbidol HCl (Umifenovir) Featured
Umifenovir is currently being investigated as a potential treatment and prophylactic agent for COVID-19 caused by SARS-CoV2 infections in combination with both currently available and investigational HIV therapies. Arbidol hydrochloride (Umifenovir hydroc
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DC11530 Tapinarof (Benvitimod; GSK2894512) Featured
Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM. Tapinarof resolves skin inflammation in mice.
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DC59016 Ensitrelvir (S-217622) Featured
S-217622 is the first oral non-covalent, non-peptidic SARS-CoV-2 3CL protease inhibitor with IC50 of 0.096 μM. S-217622 displays antiviral activity in vitro towards a range of SARS-CoV-2 variants and coronavirus families, favorable drug metabolism and pha
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DC39262 SBP-7455 Featured
SBP-7455 is an orally active dual-specific ULK1/2 autophagy inhibitor with improved binding affinity compared with SBI-0206965.
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DC31069 RBN-2397 Featured
RBN-2397 is a potent, accross species and orally active NAD+ competitive inhibitor of PARP7 (IC50<3 nM). RBN-2397 selectively binds to PARP7 (Kd=0.001 μM) and restores interferon (Type I) signaling. RBN-2397 has the potential for the study of advanced or
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DC31012 Solabegron Featured
Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of over
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DC5199 S-Ruxolitinib (INCB018424) Featured
S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.
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DC8225 Smoothened Agonist (SAG) free base Featured
SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ~ 3 nM).
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DC11735 Remdesivir(GS-5734) Featured
Remdesivir is a novel RNA-dependent RNA Polymerase,(RdRp) inhibitor. The purity of remdesivir>99.8%,signal impurity<0.05%.
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DC7493 SB1317(TG-02) Featured
SB1317(TG-02) is a novel small molecule potent CDK2/JAK2/FLT3 inhibitor with IC50s of 13/73/56 nM respectively.
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DC9873 Selonsertib(GS-4997) Featured
Selonsertib(GS-4997)is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
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DC7488 RO4987655 Featured
RO4987655(CH-4987655) is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1/MEK1 IC50=5.2 nM), with potential antineoplastic activity.
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DC11450 Selpercatinib(LOXO-292) Featured
Selpercatinib is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 163, has an IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively. Antineoplastic activity.
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DC8614 Rolapitant Featured
Rolapitant (SCH619734) is a potent, selective and orally active neurokinin NK1 receptor antagonist with a Ki of 0.66 nM.
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DC7162 SNS-314 Mesylate Featured
SNS-314 is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively.
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