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Cat. No. Product Name Field of Application Chemical Structure
DC71856 Etedesiran
Etedesiran is a Myotonin-protein kinase (MT-PK, MDPK, or DMPK) inhibitor.
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DC71855 Epirosmanol
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity.
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DC71854 DMT-5Me-dC(Bz)-CE Phosphoramidite
DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding.
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DC71853 DM-Nitrophen tertasodium
DM-Nitrophen tertasodium is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light. DM-Nitrophen tertasodium can be used for study of Ca2+ signaling.
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DC71852 DM-Nitrophen
DM-Nitrophen is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light.
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DC71851 DIBAC-GGFG-NH2CH2-Dxd
DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin derivative, is a linker-payload of protein-drug conjugates.
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DC71850 DB772 hydrate
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity.
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DC71849 Colestilan
Colestilan (MCI-196) is a non-absorbed, non-calcium-based phosphate binder and is also a non-metallic, anion exchange resin. Colestilan is orally active and can be used for hypercholesterolaemia research.
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DC71848 Cedazuridine hydrochloride
Cedazuridine (E7727) (Compound 7a) hydrochloride is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine hydrochloride can be used for cancer research.
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DC71846 Bocconoline
Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD).
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DC71845 Berberine ursodeoxycholate
Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent hypolipidemic agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.
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DC71844 Belatacept
Belatacept (BMS 224818) is a selective T-cell costimulation blocker. Belatacept binds to CD 80/86 ligands and thereby inhibits the CD-28-mediated T-cell costimulation. Belatacept can be used in the research of Immunosuppression in organ transplants.
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DC71842 AS1134900
AS1134900 is a highly selective, allosteric and uncompetitive NADP+-dependent malic enzyme 1 (ME1) inhibitor.
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DC71841 Acifluorfen-methyl
Acifluorfen-methyl is an inhibitor of the heme and chlorophyll biosynthetic enzyme protoporphyrinogen oxidase (Protox). Acifluorfen-methyl is a photobleaching herbicide.
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DC71840 5-(3-Hydroxybenzylidene)-rhodanine
5-(3-Hydroxybenzylidene)-rhodanine, a derivative of rhodanine, can be used as an algicidal agent.
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DC71839 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium
Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product generated following activation of the NADPH oxidase and lyso-PS signaling. Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium through the macrophage G2A functions to enhance existing receptor/ligand systems for resolution of neutrophilic inflammation.
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DC71838 1H-1-Ethyl Candesartan Cilexetil
1H-1-Ethyl Candesartan Cilexetil is a potential impurity found in bulk preparations of Candesartan Cilexetil.
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DC71837 16-Azidohexadecanoic acid
16-Azidohexadecanoic acid, a synthetic fatty acid, can be used as a modification marker for nucleotides and a molecular probe for fatty acid metabolism.
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DC71834 (R)-FL118
(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118. (R)-FL118 shows anticancer activity.
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DC71833 (1R,2S)-Xeruborbactam disodium
(1R,2S)-Xeruborbactam ((1R,2S)-QPX7728) disodium is a boronic acid derivative.
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DC71832 Rosiglitazone potassium
Rosiglitazone (BRL 49653) potassium is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone potassium is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone potassium can be used in the research of obesity and diabetes, senescence, ovarian cancer.
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DC71831 Pioglitazone potassium
Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone potassium can be used in diabetes research.
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DC71830 Zifcasiran
Zifcasiran is a hypoxia-inducible factor (HIF) synthesis reducer. Zifcasiran shows antitumor activities and can be used in advanced renal cell carcinoma research.
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DC71829 Mersalyl
Mersalyl (Salirgan) is a potent vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1 (HIF-1) inducer. Mersalyl induces VEGF and ENO1 mRNA expression. Mersalyl shows diuresis effects.
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DC71828 Taragarestrant
Taragarestrant (D-0502) is a potent, orally active estrogen receptor degrader. Taragarestrant has antiproliferative activity against estrogen receptor-positive breast cancer cell lines and has anticancer activity. Taragarestrant can be used for cancer research.
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DC71827 FERb 033
FERb 033 is a selective and potent ERβ agonist (Ki=7.1 nM, EC50=4.8 nM). FERb 033 shows 62-fold selectivity over ERα.
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DC71824 Tilpisertib fosmecarbil
Tilpisertib fosmecarbil is a potent serine/threonine kinase inhibitor. Tilpisertib fosmecarbil has anti-inflammatory activity.
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DC71823 Bezeparsen
Bezeparsen is a PCSK9 synthesis inhibitor.
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DC71822 CP-113818
CP-113818 is a potent cholesterol acyltransferase (ACAT) inhibitor. CP-113818 can be used for the research of Alzheimer's disease.
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DC71821 S-Adenosyl-L-methionine (p-toluenesulfonate)
S-Adenosyl-L-methionine (p-toluenesulfonate) is a naturally occurring molecule distributed to virtually all body tissues and fluids. S-Adenosyl-L-methionine takes parts in biochemical reactions involving enzymatic transmethylation, acting as a methyl group donor. S-Adenosyl-L-methionine can prevent mortality induced by Acetaminophen and acute and chronic lead poisoning in animals model. S-Adenosyl-L-methionine also possess antidepressant property.
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