CCT367766 is a potent and the third generation heterobifunctional and PROTAC-based pirin targeting protein degradation probe (PDP), depletes pirin protein expression at low concentration. CCT367766 exhibits a moderate affinity for the CRBN-DDB1 complex with an IC50 value of 490 nM. CCT367766 reveals a good affinity for the recombinant pirin and CRBN with Kd values of 55 nM and 120 nM, respectively. CCT367766 provides a potential chemical tool to study a largely unexplored protein[1].

MS1943 is a first-in-class, orally bioavailable EZH2 selective degrader, with an IC50 of 120 nM. MS1943 significantly reduces EZH2 protein levels in numerous triple-negative breast cancer (TNBC) and other cancer and noncancerous cell lines.

Thiol-PEG3-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Bromo-PEG2-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling.

C18-PEG13-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Mal-amido-PEG15-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

ML 2-14 is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. ML 2-14 can be used in the synthesis of the PROTAC.

m-PEG18-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-N-amido-PEG15-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HO-PEG18-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Acid-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

m-PEG15-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Acid-PEG12-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Biotin-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Biotin-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-Aminooxy-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Biotin-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Acid-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-N-amido-PEG10-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-amido-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Dodecylheptaglycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Acid-PEG9-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Amino-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

N-Boc-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

FmocNH-PEG3-CH2CH2NH2 (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Bromo-PEG8-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.