2-Tetralone (Beta-Tetralone) is a pro-apoptosis agent. 2-Tetralone targets MDM2 E3 ubiquitin kinase and Bcl-w anti-apoptotic protein and exhibits anticancer activity.

2-Chloro-1,3-propanediol-13C3 is the 13C-labeled 2-Chloro-1,3-propanediol. 2-Chloro-1,3-propanediol is an ester product.

2-Boc-2,6-Diazaspiro[3.3]heptane (hemioxalate) is a PROTAC linker that can be used in the synthesis of PROTACs.

2-(Aminooxy)ethanamine (dihydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.

1-Boc-4-cyanopiperidine is a PROTAC linker that can be used in the synthesis of PROTACs.

1-Boc-4-bromomethylpiperidine is a PROTAC linker that can be used in the synthesis of PROTACs.

13-Hydroxy-alpha-tocopherol is a fat-soluble vitamin E derivative and anticancer agent with antioxidant and antiproliferative activities. 13-Hydroxy-alpha-tocopherol scavenges peroxyl free radicals and protects polyunsaturated fatty acids from oxidative damage. 13-Hydroxy-alpha-tocopherol not only inhibits the growth of glioma cancer cells, but its deficiency is also closely associated with recurrent miscarriage, embryonic growth retardation and death. Clinical observations show that the expression of 13-Hydroxy-alpha-tocopherol is downregulated in the follicular fluid of patients with recurrent miscarriage. 13-Hydroxy-alpha-tocopherol has important application potential in the research of recurrent miscarriage and glioma.

13-cis Acitretin (Isoacitretin; Ro 13-7652) is a retinoid and the major in vivo metabolite of etretinate. 13-cis Acitretin is formed via in vivo isomerization of etretinate. 13-cis Acitretin serves as the primary metabolite in blood.

1,4-Bis(2-bromoethoxy)benzene is a PROTAC linker that can be used in the synthesis of PROTACs.

2-(tert-Butoxycarbonyl)-2-azaspiro[3.3]heptane-6-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

2-(4-Aminocyclohexyl)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

1,3-Bis-aminooxy propane dihydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

(S)-IP-DK143 is a polymeric micellar formulation. (S)-IP-DK143 inhibits the proliferation of cervical cancer cells, induces ROS-mediated apoptosis, and triggers mitochondrial dysfunction. (S)-IP-DK143 activates the p38 MAPK signaling pathway in cervical cancer cells, increases the phosphorylation level of p38, and slightly reduces the phosphorylation level of ERK. (S)-IP-DK143 can be used for the research of cervical cancer.

(S)-5-HT2CR agonist 1 (Compound (S)-16k) is selective 5-HT2CR agonist, with an EC50 of 14 nM. FXa-IN-2 can be used in the research of hyperlocomotion.

(R)-LY-41, R-enantiomer of LY-41, is 2-Sminotetralin derivative and 8-OH-DPAT analogue. (R)-LY-41 is a potent and selective 5-HT1A receptor agonist. (R)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (R)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (R)-LY-41 can induce the 5-HT behavioral syndrome but is weaker than (S)-LY-41. (R)-LY-41 can be used for the research of neurological disease, such as depression and anxiety.

(R)-AM-1638 is a R-isomer of AM-1638. AM-1638 is an orally active full agonist of GPR40 (EC50: 0.16 μM).

(R)-5-OH-DPAT ((R)-5-Hydroxy-DPAT) is the R-enantiomer of 5-OH-DPAT. 5-OH-DPAT is a weak antagonist of the dopamine D2 receptor (dopamine D2-receptor). 5-OH-DPAT moderately promotes sexual behavior in male rats.

(7α,24S)-7,24-Dihydroxycholest-4-en-3-one is an oxysterol.

(4-Bromobutoxy)benzene is a PROTAC linker that can be used in the synthesis of PROTACs.

(±)-U-50488 ((±)-trans-(1R,2R)-U-50488) is a selective kappa opioid receptor agonist. (±)-U-50488 can improve symptoms related to status epilepticus, but has no significant effect on spontaneous seizure episodes. (±)-U-50488 can be used for research of epilepsy.

DSPE-PEG14-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

dBET1 is a potent BRD4 protein degrader based on PROTAC technology with an EC50 of 430 nM.

KT-474 is a highly active and selective, orally bioavailable IRAK4 degrader being developed for the treatment of toll-like receptor (TLR)/interleukin-1 receptor (IL-1R)-driven immune-inflammatory diseases.

SelDeg51 (Selective Degrader of FKBP51) is a potent, selective FKBP51 PROTAC with Kd of 18 nM, Emax=90%.

BSJ-05-037 is a potent and selective heterobifunctional degrader of ITK with DC50 of 17.6-41.8 nM in TCL lines DERL-2 and Hut78. BSJ-05-037 induces potent degradation of ITK dependent on CRBN, neddylation, and the proteasome. BSJ-05-037 induces GATA-3 loss and decreases chemotherapy resistance in vitro. BSJ-05-037 disrupts TCR signaling, downregulates the Th2-associated transcription factor GATA-3, and can overcome chemotherapy resistance in TCL models in vivo.

THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Benzyl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

MS 177 (MS-177) is a potent and selective EZH2 degarder (PROTAC) based on EZH2 inhibitor C24 with CRBN ligand pomalidomide with DC50 of 0.2 uM in EOL-1 cells.MS177 effectively degraded cellular EZH2-PRC2, suppressed global H3K27me3 in leukaemia cells.MS177 exhibited half-maximal degradation concentration (DC50) values of 0.2 ± 0.1 μM and 1.5 ± 0.2 μM, and maximum degradation (Dmax) values of 82% and 68%, respectively, in EOL-1 and MV4;11 cells.MS177 efficiently suppresses EZH2-PRC2 functions, also efficiently induces Myc degradation in cancer cells, suppresses EZH2-PRC2 functions.MS177 efficiently induces leukaemia cell growth inhibition, apoptosis and cell cycle progression arrest, which is more effective than EZH2 inhibitors. MS177 (i.p. injection, 50-1 g/kg) represses AML growth without apparent toxicity in PDX models.

Benzyl-PEG1-propanol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Benzyl-PEG5-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.