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A647 | Concizumab Biosimilar(Anti-TFPI Reference Antibody) Featured |
Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that binds to the Kunitz-type protease inhibitor (KPI) 2 structural domain of TFPI, thereby blocking the interaction of this structural domain with the FXa active site. Concizumab can be used in the study of haemophilia.
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A646 | Tislelizumab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured |
Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma.
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A645 | Sintilimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured |
Sintilimab (IBI308) is a safe and effectivel humanized IgG4 monoclonal antibody that binds to PD-1 with a KD value of 74 pM. Sintilimab blocks the interaction of PD-1 with its ligands (PD-L1 and PL-L2), consequently helping to restore the endogenous antitumour T-cell response. Sintilimab combined with prebiotics inhibits tumor volume and regulates immune cell subpopulation balance in lung adenocarcinoma mice. Sintilimab can be used for the research of classical Hodgkin's lymphoma, non-small cell lung cancer and oesophageal cancer.
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A644 | Pimurutamab Biosimilar(Anti-ERBB1 / EGFR / HER1 Reference Antibody) Featured |
Pimurutamab is a humanized IgG1-κ antibody targeting EGFR. Mainly expressed by CHO-K1 cells.
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A643 | INSERM patent anti-vWF Biosimilar(Anti-vWF Reference Antibody) Featured |
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A642 | Ajinomoto patent anti-vWF Biosimilar(Anti-vWF Reference Antibody) Featured |
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A641 | LY3022856 Biosimilar(Anti-VEGFR3 / FLT4 Reference Antibody) Featured |
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A640 | Imclone 6.64 Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured |
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A639 | Alacizumab Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured |
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A638 | AT001 Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured |
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A637 | Vulinacimab Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured |
Vulinacimab (HLX-06) is an anti-VEGFR-2 monoclonal antibody (mAb). Vulinacimab can be used in the research of cancers. VEGFR-2, overexpressed in certain tumors, is critical in angiogenesis and the proliferation, survival, migration and differentiation of endothelial cells.
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A636 | Olinvacimab Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured |
Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer.
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A635 | Abbott patent anti-Flt1 Biosimilar(Anti-VEGFR1 / FLT1 Reference Antibody) Featured |
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A634 | VGX100 Biosimilar(Anti-VEGFC Reference Antibody) Featured |
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A633 | CSL346 Biosimilar(Anti-VEGFB Reference Antibody) Featured |
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A632 | Domantis patent anti-VEGF Biosimilar(Anti-VEGF Reference Antibody) Featured |
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A631 | BioMab patent anti-VEGF Biosimilar(Anti-VEGF Reference Antibody) Featured |
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A630 | Hanwha patent anti-VCAM-1 Biosimilar(Anti-VCAM1 / CD106 Reference Antibody) Featured |
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A629 | ELB-031 Biosimilar(Anti-TYRO3 Reference Antibody) Featured |
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A628 | INSERM patent anti-CO-029 Biosimilar(Anti-TSPAN8 Reference Antibody) Featured |
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A627 | Lilotomab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured |
Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity.
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A626 | AGS-67E Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured |
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A625 | Otlertuzumab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured |
Otlertuzumab (TRU-016) is a humanized anti-CD37 monoclonal antibody that can be used for cancer research.
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A624 | Naratuximab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured |
Naratuximab (Anti-TSPAN26/CD37 Reference Antibody (naratuximab)) is a humanized monoclonal antibody that binds CD37 (TSPAN26). Naratuximab can be used to synthesize an ADC compound, Naratuximab emtansine.
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A623 | Schering patent anti-TSLP Biosimilar(Anti-TSLP Reference Antibody) Featured |
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A622 | K1-70 Biosimilar(Anti-TSHR Reference Antibody) Featured |
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A621 | Flanvotumab Biosimilar(Anti-TRP1 / TYRP1 Reference Antibody) Featured |
Flanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab has potent anti-tumor activity and good tolerance.
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A620 | Sacituzumab Biosimilar(Anti-TROP2 Reference Antibody) Featured |
Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab is used for the synthesis of antibody-drug conjugates (ADC) drugs. Antibody-drug conjugates with sacituzumab (sacituzumab govitecan) (HY-132254) targeting TROP-2 have been approved for the field of triple-negative breast cancer.
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A619 | Sacituzumab govitecan Biosimilar(Anti-TROP2 Reference Antibody) Featured |
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity.
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A618 | Rinat patent anti-TrkB Biosimilar(Anti-TrkB / NTRK2 Reference Antibody) Featured |
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