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Therapeutic Antibodies

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Cat. No. Product Name Field of Application Chemical Structure
A647 Concizumab Biosimilar(Anti-TFPI Reference Antibody) Featured
Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that binds to the Kunitz-type protease inhibitor (KPI) 2 structural domain of TFPI, thereby blocking the interaction of this structural domain with the FXa active site. Concizumab can be used in the study of haemophilia.
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A646 Tislelizumab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured
Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma.
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A645 Sintilimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured
Sintilimab (IBI308) is a safe and effectivel humanized IgG4 monoclonal antibody that binds to PD-1 with a KD value of 74 pM. Sintilimab blocks the interaction of PD-1 with its ligands (PD-L1 and PL-L2), consequently helping to restore the endogenous antitumour T-cell response. Sintilimab combined with prebiotics inhibits tumor volume and regulates immune cell subpopulation balance in lung adenocarcinoma mice. Sintilimab can be used for the research of classical Hodgkin's lymphoma, non-small cell lung cancer and oesophageal cancer.
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A644 Pimurutamab Biosimilar(Anti-ERBB1 / EGFR / HER1 Reference Antibody) Featured
Pimurutamab is a humanized IgG1-κ antibody targeting EGFR. Mainly expressed by CHO-K1 cells.
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A643 INSERM patent anti-vWF Biosimilar(Anti-vWF Reference Antibody) Featured
A642 Ajinomoto patent anti-vWF Biosimilar(Anti-vWF Reference Antibody) Featured
A641 LY3022856 Biosimilar(Anti-VEGFR3 / FLT4 Reference Antibody) Featured
A640 Imclone 6.64 Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured
A639 Alacizumab Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured
A638 AT001 Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured
A637 Vulinacimab Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured
Vulinacimab (HLX-06) is an anti-VEGFR-2 monoclonal antibody (mAb). Vulinacimab can be used in the research of cancers. VEGFR-2, overexpressed in certain tumors, is critical in angiogenesis and the proliferation, survival, migration and differentiation of endothelial cells.
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A636 Olinvacimab Biosimilar(Anti-VEGFR2 / KDR / CD309 Reference Antibody) Featured
Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer.
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A635 Abbott patent anti-Flt1 Biosimilar(Anti-VEGFR1 / FLT1 Reference Antibody) Featured
A634 VGX100 Biosimilar(Anti-VEGFC Reference Antibody) Featured
A633 CSL346 Biosimilar(Anti-VEGFB Reference Antibody) Featured
A632 Domantis patent anti-VEGF Biosimilar(Anti-VEGF Reference Antibody) Featured
A631 BioMab patent anti-VEGF Biosimilar(Anti-VEGF Reference Antibody) Featured
A630 Hanwha patent anti-VCAM-1 Biosimilar(Anti-VCAM1 / CD106 Reference Antibody) Featured
A629 ELB-031 Biosimilar(Anti-TYRO3 Reference Antibody) Featured
A628 INSERM patent anti-CO-029 Biosimilar(Anti-TSPAN8 Reference Antibody) Featured
A627 Lilotomab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured
Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity.
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A626 AGS-67E Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured
A625 Otlertuzumab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured
Otlertuzumab (TRU-016) is a humanized anti-CD37 monoclonal antibody that can be used for cancer research.
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A624 Naratuximab Biosimilar(Anti-TSPAN26 / CD37 Reference Antibody) Featured
Naratuximab (Anti-TSPAN26/CD37 Reference Antibody (naratuximab)) is a humanized monoclonal antibody that binds CD37 (TSPAN26). Naratuximab can be used to synthesize an ADC compound, Naratuximab emtansine.
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A623 Schering patent anti-TSLP Biosimilar(Anti-TSLP Reference Antibody) Featured
A622 K1-70 Biosimilar(Anti-TSHR Reference Antibody) Featured
A621 Flanvotumab Biosimilar(Anti-TRP1 / TYRP1 Reference Antibody) Featured
Flanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab has potent anti-tumor activity and good tolerance.
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A620 Sacituzumab Biosimilar(Anti-TROP2 Reference Antibody) Featured
Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab is used for the synthesis of antibody-drug conjugates (ADC) drugs. Antibody-drug conjugates with sacituzumab (sacituzumab govitecan) (HY-132254) targeting TROP-2 have been approved for the field of triple-negative breast cancer.
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A619 Sacituzumab govitecan Biosimilar(Anti-TROP2 Reference Antibody) Featured
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity.
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A618 Rinat patent anti-TrkB Biosimilar(Anti-TrkB / NTRK2 Reference Antibody) Featured

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