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TCS JNK 6o(JNK Inhibitor VIII)

  Cat. No.:  DC30025   Featured
Chemical Structure
894804-07-0
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More than 5000 active chemicals with high quality for research!
Field of application
JNK Inhibitor VIII is an aminopyridine compound that inhibits JNK1, JNK2, and JNK3 with Ki values of 2, 4, and 52 nM, respectively.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 894804-07-0
Chemical Name: TCS JNK 6o
SMILES: CCOC1=C(C(=CC(=N1)NC(=O)CC2=C(C=CC(=C2)OC)OC)N)C#N
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with ki values of 2 nM, 4 nM, 52 nM, respectively[1].
Target: JNK1:2 nM (Ki) JNK2:4 nM (Ki) JNK3:52 nM (Ki)
In Vitro: JNK Inhibitor VIII (TCS JNK 6o) shows over 1000- fold selective for JNK-1 and -2 over other MAP kinases including ERK2, p38α, and p38δ[1].
References: [1]. Szczepankiewicz BG, et al. Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. J Med Chem. 2006 Jun 15;49(12):3563-80.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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