Daraxonrasib（RMC-6236） |CAS 2765081-21-6|DC Chemicals

Cas No.:	2765081-21-6
Chemical Name:	Daraxonrasib（RMC-6236）
Synonyms:	RMC6236;RAS-IN-2
SMILES:	C(N1C2=CC=C3C4=CSC(CC(C(=O)N5CCCC(N5)C(=O)OCC(C)(C)CC(C2=C3)=C1C1C=C(N2CCN(C)CC2)C=NC=1C(C)OC)NC(C1CC1C)=O)=N4)C
Formula:	C₄₄H₅₈N₈O₅S
M.Wt:	811.046928882599
Purity:	>99%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer.
Target:	KRas G12D
In Vitro:	RAS-IN-2 (Compound A122) (5 days) 抑制 AsPC-1 (K-Ras G12D) 的细胞活力，IC50 为 1-10 μM.
References:	[1]. Ethan AHLER, et al. Use of sos1 inhibitors to treat malignancies with shp2 mutations. Patent WO2022060583A1.

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