AD 2900|CAS 18360-29-7|DC Chemicals

Cas No.:	18360-29-7
Chemical Name:	2-(Hexadecylamino)-2-(hydroxymethyl)propane-1,3-diol
Synonyms:	AD 2900;2-(Hexadecylamino)-2-(hydroxymethyl)propane-1,3-diol
SMILES:	O([H])C([H])([H])C(C([H])([H])O[H])(C([H])([H])O[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
Formula:	C₂₀H₄₃NO₃
M.Wt:	345.5603
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

AD 2900 (AD2900, AD-2900) is a novel potent, broad S1P receptor antagonist with IC50 of 3.8, 3.2, 6.2, 5.9 and 0.405 uM for S1P1, 2, 3, 4 and 5 respectively; shows no significant agonism effects (EC50>50 uM); suppresses PBMC proliferation, regulates the expression of S1P1 and CCR7 on PBMCs; accumulates T cells in the blood and spleen and in turn reduces T-cell number in the lymph nodes, shows significant effects on the localization of T-cell subpopulations in mice.

COA

MSDS

Cat. No.	Product name	Field of application
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