ATF6 agonist compound A147| inhibitor of dengue and Zika virus

Cas No.:	393121-74-9
Chemical Name:	N-(2-hydroxy-5-methylphenyl)-3-phenylpropanamide
Synonyms:	AA147\|AA 147;AA-147
SMILES:	O=C(CCC1C=CC=CC=1)NC1C(O)=CC=C(C)C=1
Formula:	C₁₆H₁₇NO₂
M.Wt:	255.31
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	PNAS January 19, 2021 118 (3) eiti0221118; https://doi.org/10.1073/iti0321118. Small-molecule endoplasmic reticulum proteostasis regulator acts as a broad-spectrum inhibitor of dengue and Zika virus infections

Description:

AA147, a small molecule endoplasmic reticulum (ER) proteostasis regulator, selectively activates ATF6 arm of the unfolded protein response (UPR) extracted from patent WO2017117430A1, compound 147*[1].

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