Cas No.: | 2446817-72-5 |
Chemical Name: | APOL1-IN-1 |
Synonyms: | 1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- |
SMILES: | [C@H]1(CNC(=O)[C@H]1NC(=O)CCC1C2=C(NC=1C1=CC=C(C=C1)F)C=CC=C2)O |
Formula: | C21H20FN3O3 |
M.Wt: | 381.40 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD)[1]. |
Target: | Apolipoprotein LI (APOL1)[1] |
References: | [1]. Brodney M, et, al. Inhibitors of apol1 and methods of using same. WO2020131807A1. |