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Bucolome

  Cat. No.:  DC60281   Featured
Chemical Structure
841-73-6
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More than 5000 active chemicals with high quality for research!
Field of application
Bucolome is a CYP2C9 inhibitor, used as an uricosuric agent or anti-inflammatory agent.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 841-73-6
Chemical Name: 2,4,6(1H,3H,5H)-Pyrimidinetrione,5-butyl-1-cyclohexyl-
Synonyms: 2,4,6(1H,3H,5H)-Pyrimidinetrione,5-butyl-1-cyclohexyl-;5-butyl-1-cyclohexyl-1,3-diazinane-2,4,6-trione;1-Cyclohexyl-5-butylbarbitursaeure;5-Butyl-1-cyclohexylbarbituric acid;5-butyl-1-cyclohexyl-pyrimidine-2,4,6-trione;Bucolom;bucolome;EINECS 212-666-1;Paramidin;Paramidine
SMILES: CCCCC1C(=O)NC(=O)N(C2CCCCC2)C1=O
Formula: C14H22N2O3
M.Wt: 266.33608
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Bucolome is a CYP2C9 inhibitor, used as an uricosuric agent or anti-inflammatory agent.
In Vitro: Bucolome is a potent mixed-type inhibitor for (S)-warfarin 7-hydroxylation, with Ki of 8.2 and 20.2 μM, respectively[1].
References: [1]. Takahashi H, et al. Pharmacokinetic interaction between warfarin and a uricosuric agent, bucolome: application of In vitro approaches to predicting In vivo reduction of (S)-warfarin clearance. Drug Metab Dispos. 1999 Oct;27(10):1179-86.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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