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ALC-0315 analogue-2

Cat. No.: DC65329 Featured

Chemical Structure

2707439-64-1

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Field of application

ALC-0315 analogue-2 is an analogue of ALC-0315. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	2707439-64-1
Chemical Name:	ALC-0315 analogue-2
Synonyms:	ALC0315 analogue2， ALC 0315 analogue 2
SMILES:	O=C(C(CCCCCCCC)CCCCCC)OCCCCCCN(CCCCCCOC(C(CCCCCCCC)CCCCCC)=O)CCOCCO
Formula:	C₄₈H₉₅NO₆
M.Wt:	782.27
Purity:	ELSD-HPLC>95%
Sotrage:	1 year -20°C
Publication:	[1]. WO2022213895A1

Cat. No.	Product name	Field of application
DC65329	ALC-0315 analogue-2	ALC-0315 analogue-2 is an analogue of ALC-0315. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
DC80071	A18-Iso5-2DC18	A18-Iso5-2DC18 that could not only deliver mRNA vaccines robustly but also activate the stimulator of interferon genes (STING) pathway.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.