BAY-8400|CAS 2763602-59-9|DC Chemicals

Cas No.:	2763602-59-9
Chemical Name:	BAY-8400
Synonyms:	[1,2,4]Triazolo[4,3-a]quinoxaline, 8-[5-(difluoromethyl)-3-pyridinyl]-1-(2,3,6,7-tetrahydro-4-oxepinyl)-;GTPL11732;BAY8400;BDBM50577297;compound 25 [PMID: 34428039];8-[5-(Difluoromethyl)pyridin-3-yl]-1-(2,3,6,7-tetrahydrooxepin-4-yl)-[1,2,4]triazolo[4,3-a]quinoxali;BAY-8400;T9498;EX-A7205;G18355;AKOS040759840;8-[5-(Difluoromethyl)pyridin-3-yl]-1-(2,3,6,7-tetrahydrooxepin-4-yl)-[1,2,4]triazolo[4,3-a]quinoxaline;CS-0200337;CHEMBL4851439;HY-132293;2763602-59-9;MS-26591
SMILES:	FC([H])(C1=C([H])N=C([H])C(=C1[H])C1C([H])=C([H])C2=C(C=1[H])N1C(C([H])=N2)=NN=C1C1=C([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])F
Formula:	C₂₁H₁₇F₂N₅O
M.Wt:	393.39
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC70085	Nedisertib (Synonyms: Peposertib; M3814)	Nedisertib (M3814, MSC2490484A) is a highly potent, selective, orally bioavailable inhibitor of DNA-PK.
DC46491	BAY-8400	BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 81 nM. BAY-8400 shows synergistic activity of DNA-PK inhibition when combined with DNA damage inducing cancer therapy, like targeted alpha radiation.
DC3113	KU-0060648	KU 0060648 is a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM); with 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases.