Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC4210 | Azilsartan kamedoxomil Featured |
Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension.
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DC9380 | Cleviprex Featured |
Clevidipine(Clevidipine) is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension.
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DC9160 | Cilnidipine Featured |
Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
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DC7125 | Evacetrapib (LY2484595) Featured |
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.
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DCAPI1469 | azilsartan Featured |
Azilsartan(TAK-536) is a specific and potent angiotensin II type 1 receptor antagonist with IC50 of 2.6 nM.
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DC9185 | Candesartan cilexetil Featured |
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
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DC9623 | Flecainide (acetate) Featured |
Flecainide(Tambocor) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.
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DC2072 | LXR623 Featured |
LXR-623 is a novel Liver X Receptor modulator
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DC10947 | FPL64176 Featured |
FPL64176 is a potent L-type Ca++ channel activator with EC50 of 16 nM.
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DCAPI1442 | Atorvastatin Calcium Featured |
Atorvastatin Calcium
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DC9178 | Ketanserin Tartrate |
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DC9113 | Ketanserin |
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DC9461 | Zatebradine |
Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM.
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DC7753 | Zatebradine hydrochloride |
Zatebradine hydrochloride is a bradycardic agent that creates use-dependent inhibition of hyperpolarization-activated current (If) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres.
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DCAPI1452 | Valsartan |
Valsartan is a nonpeptide angiotensin II AT1-receptor antagonist with an IC50 ranging from 39.5 to 116 μM. This in turn causes blood vessel dilation.
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DC11138 | Guanabenz acetate |
R15A inhibitor.
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DC6903 | Lapaquistat Acetate (TAK-475) |
Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs.
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DC9443 | Otamixaban |
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.
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DC10324 | Omapatrilat |
Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with Ki values of 0.64 and 0.45 nM, respectively.
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DC9179 | Olmesartan MedoxoMil |
Olmesartan medoxomil(Olmetec; Benicar; CS 866) is an angiotensin II receptor antagonist which is used as an anti-hypertensive.
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DCAPI1464 | Olmesartan |
Olmesartan Acid is an angiotensin II receptor antagonist that prevents the binding of angiotensin II, thus preventing vasoconstriction.
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DC9108 | Nisoldipine |
Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.
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DC9170 | Nicardipine hydrochloride |
Nicardipine Hcl(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
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DC9456 | MK-0354 |
MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b.
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DC9191 | Metoprolol tartrate |
Metoprolol is a cardioselective β1-adrenergic blocking agent.
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DC11315 | Manidipine(CV-4093) |
Manidipine is a dihydropyridine L- and T-type calcium channel blocker.
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DCAPI1419 | Losartan |
Losartan is a potent, non peptide antagonist of the angiotensin II receptor type 1. This receptor initiates a signal cascade that causes vasoconstriction. Antagonism of this receptor in turn causes vasodilation by blocking the signal from angiotensin II.
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DC9123 | Lisinopril Dihydrate |
Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.
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DC10233 | Guanfacine Hydrochloride |
Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect.
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DCAPI1596 | Metroprolol succinate |
For the detailed information of Metroprolol succinate, the solubility of Metroprolol succinate in water, the solubility of Metroprolol succinate in DMSO, the solubility of Metroprolol succinate in PBS buffer, the animal experiment (test) of Metroprolol succinate, the cell expriment (test) of Metroprolol succinate, the in vivo, in vitro and clinical trial test of Metroprolol succinate, the EC50, IC50,and Affinity of Metroprolol succinate, Please contact DC Chemicals..
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