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Cell Cycle/DNA Damage

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Cat. No. Product Name Field of Application Chemical Structure
DC80086 4-Hydroxyphenylacetylglutamic acid
4-Hydroxyphenylacetylglutamic acid is a metabolite of Morus alba L.
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DC80084 4-Hydroxyalprenolol
4-Hydroxyalprenolol (Alp2b) is a metabolite of β-receptor blocker Alprenolol.
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DC80082 4E,14Z-Sphingadiene
4E,14Z-Sphingadiene is a sphosphingolipid.
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DC80106 5-HT2C agonist-13
5-HT2C agonist-13 is an orally active, selective and brain-penetrant 5-HT2C receptor agonist with human 5-HT2C receptor EC50 of 16 nM, Ki of 20 nM. 5-HT2C agonist-13 functionally activates 5-HT2C receptors, reduces food intake, reduces body weight gain, and exhibits effects reversible by a selective 5-HT2C antagonist. 5-HT2C agonist-13 can be used for the research of obesity.
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DC80073 3α,7α-Dihydroxycoprostane
3α,7α-Dihydroxycoprostane is a metabolite of cholest-4-en-3-one-7α-ol.
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DC80072 3α,7α-Dihydroxy-5β-cholestan-26-al
3α,7α-Dihydroxy-5β-cholestan-26-al is a nucleoside metabolite.
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DC80070 3-Phospho-D-glycerate
3-Phospho-D-glycerate can be converted to 2-phospho-d-glycerate (2-PGA) via phosphoglycerate mutase.
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DC80064 3-Methylcathinone hydrochloride
3-Methylcathinone (3-MMC) hydrochloride is an analogue of a psychoactive substance.
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DC80054 349U85 hydrochloride
349U85 hydrochloride is a vasodilator-cardiotonic agent.
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DC80038 2'-Deoxy-5-hydroxymethyl-CTP
2'-Deoxy-5-hydroxymethyl-CTP is a nucleoside metabolite.
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DC80030 22-Oxodocosanoic acid
22-Oxodocosanoic acid is a nucleoside metabolite.
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DC80013 1-Olein-2-myristin
1-Olein-2-myristin is an acylglycerol.
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DC80005 1-Laurin-2-olein
1-Laurin-2-olein is a glycerolipid.
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DC79999 1-Heptadecanoin-3-olein
1-Heptadecanoin-3-olein is an acylglycerol.
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DC79991 1-Arachidonin-2-palmitin-3-olein
1-Arachidonin-2-palmitin-3-olein is an acylglycerol.
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DC79980 11,14,15-THETA
11,14,15-THETA (11,14,15-Trihydroxyeicosatrienoic acid) is a nucleoside metabolite.
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DC80065 3-Methyldecane
3-Methyldecane is a fatty hydrocarbon volatile component of Ludwigia stolonifera. 3-Methyldecane can be used to study the metabolic differences in different parts of this aquatic plant.
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DC79959 1,3-Dibutyrin
1,3-Dibutyrin is a glycerolipid.
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DC79939 1,10-Bis(methylsulfinyl)decane
1,10-Bis(methylsulfinyl)decane (Compound IIf) is a decamethonium analogue and is a non-electrolytic sulfoxide compound. 1,10-Bis(methylsulfinyl)decane has low lethal (LD50 >37.5 mg/kg) effect in mice and neuromuscular blocking (ED50 >7 mg/kg) effects in cat.
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DC79923 (S)-Bleximenib
(S)-Bleximenib (Compound 28) ((S)-JNJ-75276617) is an isoform of Bleximenib. (S)-Bleximenib shows an IC50 greater than 1 μM in the MEIS1 mRNA expression assay. (S)-Bleximenib can be used in the research of acute myeloid leukemia.
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DC79911 (R)-Ureidoisobutyric acid
(R)-Ureidoisobutyric acid is a nucleoside metabolite.
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DC79891 (3S,5S)-3,5-Diaminohexanoate
(3S,5S)-3,5-Diaminohexanoate ((3S,5S)-DAH) is a nucleoside metabolite.
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DC79887 (2S)-2-Isopropyl-3-oxosuccinate
(2S)-2-Isopropyl-3-oxosuccinate ((2S)-2-Isopropyl-3-oxosuccinic acid) is a nucleoside metabolite.
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DC77840 Emzadirib
Emzadirib, an inhibitor of RAD51, exhibits a reduction in RAD51 foci. This compound displays significant anti-tumor activity with tumor growth inhibition in in vivo and in vitro models.
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DC77839 Ribociclib succinate hydrate
Ribociclib succinate hydrate is an orally bioavailable and selective, inhibitor of both CDK4 and CDK6 with IC50 values of 10 nM and 39 nM, respectively. It exhibits anticancer activitiy and can be used in breast cancer, melanoma, liposarcoma, non–small cell lung cancer, and neuroblastoma therapy research.
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DC77838 PolQi2
PolQi2 is a PolΘ inhibitor that specifically targets the N-terminal helicase domain of PolΘ, thereby suppressing alt-EJ (alternative end-joining) repair. This compound improves the accuracy and integration efficiency of gene editing across multiple loci and diverse cell lines. Additionally, it demonstrates synergistic effects with DNA-PK inhibitors in reducing Cas9-mediated off-target activity. Its application is suitable for gene editing studies.
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DC77827 BSJ-5-63
BSJ-5-63 is a potent PROTAC degrader of CDK12, CDK7, CDK9. BSJ-5-63 decreases the protein expression of CDK12, CDK7, CDK9, RNAPII, Cyclin K, while also suppressing the mRNA expression of BRCA1 and BRCA2. BSJ-5-63 demonstrates anticancer properties and has the potential for the research of prostate cancer.
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DC47131 Camonsertib Featured
Camonsertib is a potent ATR inhibitor. ATR inhibitor 4 has antitumor activity.
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DC70085 Nedisertib (Synonyms: Peposertib; M3814) Featured
Nedisertib (M3814, MSC2490484A) is a highly potent, selective, orally bioavailable inhibitor of DNA-PK.
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DC76263 Mal-Exatecan Featured
Mal-Exatecan is a Mal (Maleimide) modified Exatecan. Rilpivirine is an effective and selective diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). It exhibits potent antiviral activity against both wild-type HIV (EC50 = 0.4 nM) and mutant strains (EC50 = 0.1-2.0 nM).
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