Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC7976 | CID 797718 Featured |
CID-797718 is a compound with unknown details.
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DC9955 | BCL6 inhibitor(CID5721353) Featured |
CID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor).
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DC7253 | CID-2011756 Featured |
CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells.
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DC10873 | CID16020046 Featured |
CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist; inhibitsGPR55 constitutive activity with IC50 of 0.15 uM.
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DC2060 | CI994 (Tacedinaline) Featured |
CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 μM.
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DC8139 | GMX1778(CHS-828) Featured |
CHS-828 is a pyridyl cyanoguanidine anti-tumor agent that has been identified as a competitive inhibitor of Nampt as well as an inhibitor of NF-κB pathway activity.
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DC8116 | Tosedostat (CHR2797) Featured |
CHR-2797 is an aminopeptidase inhibitor, with IC50 values of 100 nM for LAP3 (LAP), 150 nM for PSAP (PuSA) and 220 nM for CD13 (Aminopeptidase N).
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DC9082 | Chlorpromazine HCl Featured |
Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug.
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DC7384 | CHIR-98014 Featured |
CHIR-98014 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
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DC9292 | CHIR-090 Featured |
CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin.
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DC7978 | Tucidinostat(Chidamide) Featured |
Chidamide is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM); no inhibition on HDAC4/5/7/9/6(IC50>30 uM).
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DC7383 | CH5424802(Alectinib) Featured |
CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation.
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DC7939 | CH-223191 Featured |
CH-223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.
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DC10722 | CGP-71683A Featured |
CGP 71683A is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity.
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DC7381 | CGP-57380 Featured |
CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 (IC50 = 2.2 μM) with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases.
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DC10843 | CGP 52432 Featured |
CGP 52432 is a potent, selective GABAB receptor antagonist (IC50 = 85 nM).
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DC7101 | CGK733 Featured |
CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM.
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DC7039 | CFTR Inhibitor II Featured |
CFTR Inhibitor II is a cell-permeable glycinyl hydrazone compound that acts as a potent, selective and reversible open-channel blocker of CFTR with intermediate speed (< 1 min; 95% inhibition at 50 µM; Ki = 4.3 µM in CFTR-expressing FRT cells.
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DC7814 | Cerdulatinib(PRT-062070; PRT2070) Featured |
Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor.
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DC9765 | CERC-501(LY-2456302,Aticaprant) Featured |
CERC-501(LY-2456302) is a potent, selective antagonist of the kappa opioid receptor (KOR) (Ki = 0.81 nM vs. 24.0 nM and 155 nM for the μ-opioid receptor (MOR) and δ-opioid receptor (DOR), respectively.
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DC10337 | CEP-40783 Featured |
CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
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DC11078 | Cenupatide Featured |
Cenupatide is an urokinase plasminogen activator receptor (uPAR) inhibitor drug candidate. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of streptozotocin (STZ)-induced diabetes. Cenupati
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DC32353 | Cenicriviroc Mesylate Featured |
Cenicriviroc, also known as TAK-652 and TBR-652, is an experimental drug candidate for the treatment of HIV infection. It is being developed by Takeda Pharmaceutical and Tobira Therapeutics. Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowi
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DC10316 | Cenicriviroc Featured |
Cenicriviroc is an orally active, dual CCR2/CCR5 antagonist, and displays potent anti-inflammatory and aninfective activity.
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DCAPI1491 | Celecoxib Featured |
Celecoxib is a selective Cox-2 inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LM
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DCAPI1155 | Celastrol Featured |
Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.
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DC3170 | Cediranib Featured |
Cediranib (AZD2171) is a highly potent VEGFR2 inhibitor with IC50 of 0.5 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM.
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DC10792 | DIM-C-pPhOCH3(C-DIM5) Featured |
C-DIM5 is a Nur77 agonist. Activation of the orphan nuclear receptor Nur77 by C-DIM5 is associated with decreased cancer cell survival,
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DC8361 | CDDO(Bardoxolone; RTA 401) Featured |
CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM.
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DC10491 | CD437 Featured |
CD437 is a synthetic retinoid that is an RARγ-selective agonist. It displays RARγ-dependent and -independent effects on differentiation and apoptosis.
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