Cat. No. | Product Name | Field of Application | Chemical Structure |
---|---|---|---|
DC23194 | MRT-68921 hydrochloride Featured |
MRT-68921 hydrochloride (MRT68921) is a potent, relatively specific inhibitor of both ULK1 and ULK2 with IC50 of 2.9 and 1.1 nM, respectively.
More description
|
![]() |
DC1076 | Otenabant(CP945598.HCl) Featured |
CP-945598 HCl is a potent and selective cannabinoid type 1 receptor antagonist with Ki of 0.7 nM.
More description
|
![]() |
DC26153 | PDM-11 Featured |
PDM 11 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
More description
|
![]() |
DC7611 | PF 3845 Featured |
PF 3845 is a selective fatty acid amide hydrolase (FAAH) inhibitor (Ki = 0.23 uM).
More description
|
![]() |
DC26158 | Pirozadil Featured |
Pirozadil is a hypolipidemic agent.
More description
|
![]() |
DC10851 | PK11000 Featured |
PK11000 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 by covalent cysteine modification, without compromising DNA binding.
More description
|
![]() |
DC26149 | PK11007 Featured |
PK11007 is a thiol-reactive anticancer agent that stabilizes wild type and mutant p53 through selective alkylation of two surface cysteines without interfering with its DNA binding.
More description
|
![]() |
DC12601 | PXS-5153A Featured |
PXS-5153A (PXS5153A) is a potent, selective, fast-acting, dual LOXL2/LOXL3 inhibitor with IC50 of <40 nM against all mammalian species LOXL2, inhibits human LOXL3 with IC50 of 63 nM.
More description
|
![]() |
DC11369 | SPHINX31 Featured |
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50 = 5.9 nM).
More description
|
![]() |
DC26159 | SRI-011381 Featured |
SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease.
More description
|
![]() |
DC9926 | XMU-MP-1 Featured |
XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM against MST1 and MST2, respectively.
More description
|
![]() |
DC26155 | Sulfaphenazole Featured |
Sulfaphenazole is an inhibitor of CYP2C9 (Ki = 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Kis = 63 and 29 μM for CYP2C8 and CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19).
More description
|
![]() |
DC26142 | SRT-3109 Featured |
SRT3109 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases.
More description
|
![]() |
DC26157 | PKC-theta inhibitor Featured |
PKC-theta inhibitor is a selective PKC-θinhibitor, with an IC50 of 12 nM.
More description
|
![]() |
DC26152 | PIK-75 free base Featured |
PIK-75 is a selective cell-permeable inhibitor of PI 3-kinase p110α (IC50 values are 5.8, 76 nM and 1.3 μM at PI 3-kinase p110α, PI 3-kinase p110γ and PI 3-kinase p110β respectively). Inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of
More description
|
![]() |
DC26167 | ICA 110381 (Compound 16) Featured |
ICA 110381 (Compound 16) is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy. ICA 110381 is a KCNQ2/Q3 agonist (EC50=0.38 μM) as well as KCNQ1 antagonist (IC50=15 μM).
More description
|
![]() |
DC26164 | GW284543 (UNC10225170) Featured |
GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 (UNC10225170) reduces pERK5, and decreases endogenous MYC protein.
More description
|
![]() |
DC26146 | Fluorofenidone Featured |
Fluorofenidone is an inhibitor of nicotinamide adeninedinucleotide phosphate oxidase via PI3K/Akt pathway in the pathogenesis of renal interstitial fibrosis.
More description
|
![]() |
DC26143 | FGH10019 Featured |
FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM.
More description
|
![]() |
DC26160 | Ethosalamide Featured |
Etosalamide, also known as Ethosalamide, is an antipyretic and analgesics agent.
More description
|
![]() |
DC26163 | DMNQ Featured |
DMNQ is a redox cycling agent that generates both superoxide and hydrogen peroxide intracellularly in a concentration dependent manner. DMNQ increases ROS generation.
More description
|
![]() |
DC26156 | ARN 272 Featured |
ARN 272 is a fAAH-like anandamide transporter (FLAT) inhibitor (IC50 = 1.8 μM); cytosolic variant of FAAH-1 that binds anandamide.
More description
|
![]() |
DC26174 | Adenosine Amine Congener Featured |
Adenosine Amine Congener is shown to be an aqueous-soluble Adenosine A1-R agonist.
More description
|
![]() |
DC26176 | AM 92016 Featured |
A specific blocker of the time dependent delayed rectifier potassium current, devoid of any β-adrenoceptor blocking activity. Exhibits proarrhythmic and prohypertensive activity in vivo.
More description
|
![]() |
DC26144 | A 438079 Featured |
A 438079 is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.
More description
|
![]() |
DC8902 | PNU282987 Featured |
![]() |
|
DC12201 | NADP Featured |
![]() |
|
DC11144 | NBI-59159 Featured |
![]() |
|
DC26165 | 1-BCP Featured |
1-BCP is a centrally active drug that modulates AMPA receptor gated currents. 1-BCP is a memory-enhancing agent.
More description
|
![]() |
DC26137 | 2-HBA Featured |
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
More description
|
![]() |