Cat. No. | Product Name | Field of Application | Chemical Structure |
---|---|---|---|
DC72521 | Levonadifloxacin |
Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains.
More description
|
![]() |
DC72496 | CMX-2043 |
CMX-2043 is a novel analogue of α-Lipoic Acid. CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model.
More description
|
![]() |
DC72456 | (+)SHIN2 |
(+)SHIN2 is a serine hydroxymethyltransferase (SHMT) inhibitor, whose target can be traced with 13C-serine. (+)SHIN2 increases survival in NOTCH1-driven mouse primary acute lymphoblastic leukemia (T-ALL) in vivo with a synergistic effect with Methotrexate.
More description
|
![]() |
DC72449 | MRV03-069 |
MRV03-069 (Compound 3) is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin on eukaryotic cells. MRV03-069 can be used in colorectal cancer research.
More description
|
![]() |
DC72444 | MRV03-068 |
MRV03-068 (Compound 2) is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin on eukaryotic cells. MRV03-068 can be used in colorectal cancer research.
More description
|
![]() |
DC72441 | CPUL1 |
CPUL1 is a TrxR inhibitor, which shows proliferation-inhibitory and anti-metastatic activity against A549 cells. CPUL1 influences EMT (epithelial-mesenchymal transition) via inducing ROS-mediated ERK/JNK signaling by inhibiting TrxR1 enzyme activity.
More description
|
![]() |
DC72435 | (R)-Asundexian |
(R)-Asundexian ((R)-BAY-2433334) is the enantiomer of Asundexian. (R)-Asundexian can be used in studies of cardiovascular disease (especially thrombotic or thromboembolic disease), edema, and ophthalmic disease.
More description
|
![]() |
DC72381 | α-Demethylnaproxen |
α-Demethylnaproxen is the major metabolite of Nabumetone, Nabumetone is an orally active COX-2 inhibitor with anti-inflammatory activity.
More description
|
![]() |
DC72333 | Cetirizine methyl ester |
Cetirizine methyl ester is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist.
More description
|
![]() |
DC72332 | Cipralisant (enantiomer) |
Cipralisant (GT-2331) enantiomer is the enantiomer of Cipralisant, Cipralisant is an orally active, potent, selective, and high affinity histamine H3 receptor antagonist (rat Ki=0.47 nM).
More description
|
![]() |
DC72313 | Dideoxy-amanitin |
Dideoxy-amanitin (compound 2), an α-Amanitin derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC50 value of 74.2 nM.
More description
|
![]() |
DC72280 | PNU-101603 |
PNU-101603 is a metabolite of Sutezolid. PNU-101603 has excellent activity against Mycobacterium tuberculosis (MTB).
More description
|
![]() |
DC72562 | MeTC7 |
MeTC7 is a Vitamin-D receptor (VDR) antagonist. MeTC7 has potent VDR inhibition activity with an IC50 value of 2.9 μM. MeTC7 shows good antitumor effects.
More description
|
![]() |
DC72560 | ZZL-7 |
ZZL-7 is a fast-onset antidepressant agent. ZZL-7 works by disrupting the interaction between the serotonin transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN). ZZL-7 can cross the blood-brain barrier readily. ZZL-7 can be used for the research of major depressive disorder (MDD).
More description
|
![]() |
DC72557 | Pyrazoloadenine |
Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity.
More description
|
![]() |
DC72556 | NCGC00188636 |
NCGC00188636 is a novel covalent pyruvate kinase (PYK) inhibitor. NCGC00188636 blocks nucleotide binding to the active site of pyruvate kinase. NCGC00188636 can be used for the research of the metabolism of many organisms and cell types.
More description
|
![]() |
DC72555 | Z-Pro-prolinal |
Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) is a specific, orally active prolyl endopeptidase (PREP) inhibitor with an IC50 of 0.4 nM for porcine PREP.
More description
|
![]() |
DC72554 | PKI(5-22)amide |
PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the cyclic AMP-dependent protein kinase (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors.
More description
|
![]() |
DC72552 | Reversin 121 |
Reversin 121 is a P-glycoprotein inhibitor. Reversin 121 increases the ATPase activity of MDR1. Reversin 121 reverses P-glycoprotein-mediated multidrug resistance. Reversin 121 can be used in the research of cancers.
More description
|
![]() |
DC72550 | NecroIr1 |
NecroIr1 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin-resistant lung cancer cells (A549R). NecroIr1 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr1 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and Mixed Lineage Kinase (MLKL), and regulates CDK4 expression.
More description
|
![]() |
DC72548 | GN25 |
GN25 is a specific p53-Snail binding inhibitor with antitumor effects.
More description
|
![]() |
DC72547 | C16-Ceramide |
C16-Ceramide is a natural small molecule activating p53 through the direct and selective binding.
More description
|
![]() |
DC72545 | MK-571 sodium salt |
MK-571 sodium salt (L-660711) is a selective, orally active antagonist of leukotriene D4 receptor. It is also an inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1).
More description
|
![]() |
DC72544 | Myelopeptide-2 |
Myelopeptide-2 is a peptide originally isolated from the supernatant of porcine bone marrow cell cultures, can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. Myelopeptide-2 also recover depressed interleukin-2 (IL-2) synthesis and interleukin-2 receptor (IL-2R) expression. Myelopeptide-2 involves in immunity homeostasis, is perspective to be applied in antitumor and antivirus research.
More description
|
![]() |
DC72543 | CL-197 |
CL-197 is an orally active and long-acting purine anti-HIV nucleoside reverse transcriptase inhibitor (NRTI). CL-197 has potential effect on the research of viral, oncological and cerebrovascular diseases.
More description
|
![]() |
DC72542 | XZ426 |
XZ426 is a potent integrase strand transfer inhibitor with anti- < a href="https://www.medchemexpress.cn/Targets/HIV.html" class="link-product" target="_blank">HIVactivity.
More description
|
![]() |
DC72541 | MM-401 TFA |
MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia.
More description
|
![]() |
DC72539 | RL-0070933 |
RL-0070933 is a potent smo cilial modulator with an EC50 value of 0.02 µM. RL-0070933 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway.
More description
|
![]() |
DC72538 | GS-9256 |
GS-9256 is a selective HCV NS3 protease inhibitor. GS-9256 has good pharmacokinetic properties and antiviral activity.
More description
|
![]() |
DC72537 | (R,S)-3,5-DHPG Hydrochloride |
(R,S)-3,5-DHPG hydrochloride (DHPG, Dihydroxy phenylglycine) is a salt of free amino acid dihydroxy phenylglycine (DHPG) which acts as a selective and potent agonist of group I metabotropic glutamate receptors (mGluR) (mGluR 1 and mGluR 5).
More description
|
![]() |