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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC34738 SMPB Crosslinker
SMPB crosslinker, or N-Succinimidyl 4-[4-maleimidophenyl]butyrate, is a heterobifunctional protein crosslinking reagent that is reactive toward sulfhydryl and amino groups. SMPB crosslinker's spacer arm is non cleavable. The SMPB protein crosslinker is an extended chain length analog of MBS crosslinker.
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DC34731 GMBS Crosslinker
GMBS crosslinking reagent, also known as N-(Gamma-Maleimidobutyryloxy) Succinimide, is a non-cleavable, water insoluble, heterobifunctional protein crosslinker. GMBS crosslinking reagent is commonly used to crosslink haptens to carrier proteins or enzymes to antibody. GMBS crosslinking reagent's short spacer arm length of 7.3 angstroms and is less immunogenic than the MBS crosslinking reagent analog. GMBS crosslinking occurs via NHS ester and maleimide reactive groups which react with amino and sulfhydryl moites, respectively. GMBS Crosslinker is useful for making antibody drug conjugates (ADCs).
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DC34700 Dagadip
Carbophenothion is an organophosphoric insecticide that is hamrful to livestock.
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DC34698 Phenaglycodol
Phenaglycodol is a tranquilizing agent previously used to treat a variety of nervous conditions and tensions including anxiety and depression. It has also been effective as an anticonvulsive agent against seizures.
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DC34682 Sulfometuron-methyl
Sulfometuron-methyl is a herbicide that also is an active antibacterial agent. Sulfometuron-methyl is a potent inhibitor of acetolactate synthase II and thus exhibits antibacterial properties.
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DC34660 Perthane
Perthane is the diethyl derivative of common pesticide DDD. It may prevent the formation of spontaneous mammary carcinoma, and also may causes adrenocortical atrophy in humans.
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DC34613 Ac Phe-NH2
Ac-Phe-NH2 is a non-competitive inhibitor (Ki = 8 ± 1.2 mM) of polyubiquitin chain elongation by destabilizing the active trimer.
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DC34611 Betaine Aldehyde Chloride
Betaine Aldehyde Chloride is an inhibitor of anaerobic choline metabolism by human gut bacteria.
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DC34593 ADX-10059 Hydrochloride
ADX10059 Hydrochloride is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator.
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DC34553 360-A
360A is a stabilizing G-Quadruplex ligand which has potent selectivity toward G-quadruplex structures of the telomeric 3'-overhang.
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DC34546 Grifolic acid
Grifolic acid is a natural inhibitor of the alpha-linolenic acid (LA)-induced ERK and [Ca(2+)](i) responses in GPR120-expressing cells, and a promotor of ERK and [Ca(2+)](i) responses in GPR120-expressing cells.
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DC34514 20-Hydroxyeicosatetraeonic acid
20-HETE is a lipid mediator which activates the transcription of ACE via NFkB translocation and promoter binding. This causes detrimental effects in cerebral circulation, and modulating KCa3.1 channels.
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DC34507 CyPPA
CyPPA is a positive modulator of SK3 and SK2, which reduces the activity of dopaminergic neurons. CyPPA inhibits dopamine release, and counteracts hyperdopaminergic behaviors induced by methylphenidate.
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DC34493 Myxothiazol
Myxothiazol is an inhibitor of mitochondrial respiratory chain complexes III. Myxothiazol induces transcription of the p53-responsive SESN2 gene that plays an important role in stress response and homeostatic regulation.
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DC34476 MS0015203
MS0015203 is a potent and selective agonist of the neuropeptide receptor GPR171.
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DC34460 C8 Ceramide
C8 Ceramide is a cell-permeable analog of naturally occurring ceramides.
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DC34445 Ranitidine-N-oxide
Ranitidine-N-oxide is a metabolite of Ranitidine. Ranitidine is a histamine H2-receptor antagonist, inhibiting the normal and meal-stimulated secretion of stomach acid. Ranitidine, sold under the trade name Zantac among others, is a medication which decreases stomach acid production.
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DC34439 5-CFDA
5-CFDA is a cell membranes permeatable non-fluorescent prodrug of 5-carboxyfluorescein. It shows strongly fluorescent to differentiate viable cells from apoptotic cells after being enzymatically hydrolyzed inside cells.
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DC34436 XRP44X
XRP44X is a potent Ras-Net (Elk-3) pathway inhibitor.
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DC34402 MB-3
MB-3 is a histone acetyltransferase GCN5 inhibitor.
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DC34393 BVT.13
BVT.13 is a selective PPAR-gamma activator.
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DC34382 YN1
YN1 is a PFKFB3 inhibitor.
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DC34316 Rubone
Rubone is a modulator of the tumor suppressor miRNA-34a. It acts by inhibiting the growth of hepatocellular carcinoma.
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DC34283 Quinpirole dihydrochloride
Quinpirole dihydrochloride is a D2-like dopamine receptor agonist.
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DC34277 Lovastatin Sodium
Lovastatin Sodium is an inhibitor of HMG-CoA reductase.
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DC34248 SKF-10047
SKF-10047 is a sigma-1 receptor agonist.
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DC34239 Trimosulfa
Trimosulfa is a fixed antibiotic combination. It is widely used for mild-to-moderate bacterial infections and as prophylaxis against opportunistic infections.
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DC34211 NDM-1 inhibitor-1
NDM-1 inhibitor-1 is an inhibitor of new delhi metallo-β-lactamase-1 (NDM-1). New Delhi Metallo-β-Lactamase-1 (NDM-1) has drawn great attention due to its diverse antibiotic resistant activity.
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DC34208 FSBA
FSBA is a covalent inhibitor of anthrax edema factor.
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DC34206 Doxazosin Mesylate
Doxazosin Mesylate is an alpha-Adrenergic receptor blocker.
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