Metabolite of Resveratrol

Red-absorbing, water-soluble, and iodinated resorufin derivative, being selectively activated with a monoamine oxidase (MAO) enzyme, showing high 1O 2 generation yields in aqueous solutions upon addition of MAO isoforms

Angiotensin-converting enzyme 2 (ACE2) activator, acting as a modulator on RAAS and KKS activation during COVID-19

Potent VR1 vanilloid receptor agonist, activating protein kinase C

Oxidation-reduction indicator in cell viability

Selective 5-HT1A receptor agonist

Novel bacterial methionyl t-​RNA synthetase (MRS) inhibitor, hampering Plasmodium growth very effectively

5-HT3 antagonist and 5-HT4 agonist, also acting as a 5-HT2B antagonist

Potent ultra short-acting synthetic unique opioid analgesic

Novel selective antagonist of the mGlu5 receptor

Novel specific inhibitor of the ability of RegA to activate its target promoters, reducing expression of a number of proteins required for virulence

Novel inhibitor of the supercoiling and ATPase reactions of DNA gyrase, inhibiting gyrase by preventing the binding of ATP and showing selectivity against M. smegmatis.

Novel potent inhibitor of the supercoiling and ATPase reactions of DNA gyrase, inhibiting gyrase by preventing the binding of ATP

Novel Prenyltransferase Inhibitor with In Vitro and In Vivo Antibacterial Activity

Novel potent inhibitor of RECQL5-helicase activity, and stabilizing RECQL5-RAD51 physical interaction, leading to impaired HRR and preferential killing of RECQL5-expressing breast cancer

Novel HIV-1 Integrase Inhibitor

Novel HIV-1 Integrase Inhibitor

Novel Potent Broad-Spectrum Inhibitor of Influenza A Virus RNA-Dependent RNA Polymerase (RdRp)

Novel highly potent, selective, and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth

Selective inhibitor of poly(ADP-Ribose) glycohydrolase (PARG)

Novel dual inhibitor of dihydroceramide desaturase (dhCerDS) and acid ceramidase (ACDase)

Novel dual inhibitor of dihydroceramide desaturase (dhCerDS) and acid ceramidase (ACDase)

Potent fluorescent α4β1/α9β1 inhibitor

Novel metabotropic glutamate type 5 (mGlu5) receptor negative allosteric modulator (NAM)

Novel inhibitor of geranylgeranyl diphosphate synthase (GGDPS)

Novel inhibitor of geranylgeranyl diphosphate synthase (GGDPS), showing significant reduction in tumor growth in mice

Novel potent inhibitor of p38 MAPK

Novel inhibitor of the tyrosine kinase BCR-ABL and platelet-derived growth factor receptor, inhibiting mitosis entry in acute myeloid leukemia cells via suppression of Aurora kinase A expression

Hsp90 N-terminal inhibitor

Potent anti-free radical agent, elevating glutathione peroxidase (GSH-PX) and super oxide dismutase (SOD) levels and lowering malonaldehyde (MDA) level in vivo in the Alzheimer's model