Dual thromboxane synthase inhibitor and thromboxane receptor antagonist

Original TXA2 modulator, inhibiting the action of thromboxane A2 and 8-iso-prostaglandin F2alpha

Inhibitor of Marburg virus (MARV) growth at noncytotoxic concentrations

Inhibitor of calpain, cathepsin L and cathepsin B

Novel ERK inhibitor, inducing breast cancer cell apoptosis via mitochondrial pathway but independent on Ras/Raf/MEK pathway

Potent 14-3-3 inhibitor

Natural Potent 14-3-3 inhibitor

Natural anti-coronavirus agent

Bradykinin antagonist, causing impressive growth inhibition of lung and prostate tumors, displaying superior in vivo inhibitory effects than convential chemotherapeutic drugs

Novel inhibitor of the expression of anti-apoptotic protein survivin and membrane-bound efflux pump ATP binding cassette B 1 (ABCB1, p-glycoprotein), presumably via signal transducer and activator of transcription 3 (Stat3), inhibiting human prostate canc

Novel effective inhibitor of survivin expression at both the mRNA and protein levels in vitro, significantly reducing survivin in bone metastatic C4-2 tumors

Novel inhibitor of survivin transcription through a signal transducer and activator of transcription 3 (Stat3)-dependent mechanism, inhibiting tissue expression of survivin and inducing apoptosis in C4-2 skeletal tumor

Novel potent and selective bumped kinase inhibitor (BKI) CpCDPK1 IC 50 0.005 µM

Novel potent and selective bumped kinase inhibitor (BKI) CpCDPK1 IC 50 0.0025 µM

Novel Bumped-Kinase Inhibitor (BKI) for Cryptosporidiosis Therapy

Novel Bumped-Kinase Inhibitor (BKI) for Cryptosporidiosis Therapy

Novel potent and selective covalent Pin1 inhibitor

Potent inhibitor of recombinant human and mouse Transglutaminase enzyme activity, mainly TG2 and the close related enzyme TG1

Potent and selective dual inhibitor of MEK5 and ERK5

Novel potent antagonist of RORγt function, displaying an increased selectivity for RORγt over RORα and PPARγ compared to the purely orthosteric and allosteric non-PEG-linked parent compounds

Inactivator of GSTP1>GST P1-1 through the covalent modification of two Cys47 residues per dimer and one Cys101

Novel Orally Efficacious Pan-HDAC Inhibitor

Potent activator of the Neh2-luc reporter

UV stabilizer

Novel inhibitor of LPS-induced inflammation in macrophages, improving survival in sepsis

Novel and selective Wnt signaling inhibitor

Novel inhibitor of angiogenesis by regulating STAT3 and VEGF in breast cancer cells

Selective hAMCase Inhibitor

Novel anti-HIV active dimeric prodrug of 2‘,3‘-dideoxy-2‘,3‘-didehydrothymidine monophosphate (d4TMP)

Class I antiarrhythmic agent with chronotropic, inotropic, dromotropic and coronary vasodilator effects, potently blocking sodium channel