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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC76452 Azidoindolene 1
Azidoindolene 1 is structurally similar to cannabinoid.
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DC76451 APP-FUBINACA
APP-FUBINACA is a cannabinoid receptor agonist and a derivative of phenylalaninamide-based indazole-3-carboxamide. APP-FUBINACA exhibits neurostimulatory effects.
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DC76450 Afubiata
Afubiata is structurally similar to known synthetic cannabinoids.
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DC76449 ADB-BINACA
ADB-BINACA is categorized as a synthetic cannabinoid.
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DC76448 ADB-BICA
ADB-BICA is structurally classified as a synthetic cannabinoid.
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DC76447 AB-FUBINACA 3-fluorobenzyl isomer
AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid that belongs to the indole derivatives and has a high affinity for the central CB1 receptors (Ki= 0.9 nM), exhibiting anticonvulsant activity.
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DC76446 AB-FUBICA
AB-FUBICA (Compound 13) is a CB1 and CB2 receptor agonist that activates G-protein coupled inwardly rectifying potassium channels (GIRK) by binding to CB1 and CB2 receptors, displaying notable cannabinoid-like activity. AB-FUBICA has EC50 values of 21 nM for CB1 and 15 nM for CB2. AB-FUBICA may be suitable for studying pain management, neurodegenerative diseases, and inflammation-related mechanisms.
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DC76445 ABD459
ABD459 is a CB1 receptor antagonist with significant effects on regulating food intake and sleep-wake cycles. ABD459 completely displaces CB1 agonist CP99540 (Ki = 8.6 nM) and antagonizes CP55940-induced GTPγS binding (KB = 7.7 nM). ABD459 may specifically modulate endogenous cannabinoid release through cholinergic activity and plays a role in attention and arousal regulation. ABD459 is suitable for research in neurological disorders.
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DC76444 8β-Hydroxy-exo-THC
8β-Hydroxy-exo-THC is a cannabinoid ether analogue with a weaker affinity for receptor sites, with an IC50 of 1.2 μM.
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DC76443 6',7'-Epoxy cannabigerol
6',7'-Epoxy cannabigerol is a phytocannabinoid metabolite.
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DC76442 5'-Hydroxy-9(S)-hexahydrocannabinol
5'-Hydroxy-9(S)-hexahydrocannabinol is structurally similar to known phytocannabinoids.
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DC76441 5'-Hydroxy-9(R)-hexahydrocannabinol
5'-Hydroxy-9(R)-hexahydrocannabinol is a phytocannabinoid metabolite.
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DC76440 5-Fluoro THJ
5-Fluoro THJ is a derivative of THJ-018. THJ-018 is a synthetic cannabinoid.
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DC76439 3-CAF
3-CAF is a synthetic cannabinoid featuring a 3-carboxylate-indazole structure.
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DC76438 2-Fluoro QMPSB
2-Fluoro QMPSB (QMDFPSB) is structurally similar to known synthetic cannabinoids.
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DC76437 11-Hydroxy-9(S)-hexahydrocannabinol
11-Hydroxy-9(S)-hexahydrocannabinol is a phytocannabinoid metabolite.
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DC76436 11-Hydroxy-9(R)-hexahydrocannabinol
11-Hydroxy-9(R)-hexahydrocannabinol is a phytocannabinoid metabolite.
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DC76435 10α-Hydroxy-Δ8-THC
10α-Hydroxy-Δ8-THC (10α-Hydroxy-Δ8-tetrahydrocannabinol) is a phytocannabinoid.
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DC76434 (±)-CBCP
(±)-CBCP ((±)-Cannabichromephorol) is structurally similar to known phytocannabinoids.
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DC76433 (±)-Cannabichromeorcin
(±)-Cannabichromeorcin is a cannabinoid.
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DC76432 (±)-Cannabichromebutolic acid
(±)-Cannabichromebutolic acid is structurally similar to known phytocannabinoids.
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DC76431 (±)-9α-Hydroxy hexahydrocannabinol
(±)-9α-Hydroxy hexahydrocannabinol ((±)-9α-Hydroxy HHC) is structurally similar to known phytocannabinoids.
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DC76430 (±)-8'-Hydroxy cannabichromene
8'-Hydroxy cannabichromene is a phytocannabinoid metabolite.
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DC76429 (±)-6',7'-Epoxy cannabichromene
(±)-6',7'-Epoxy cannabichromene is a phytocannabinoid metabolite.
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DC76428 (±)-6',7'-Dihydroxy cannabichromene
(±)-6',7'-Dihydroxy cannabichromene is a phytocannabinoid metabolite.
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DC76427 (-)-7-Nor-7-carboxy cannabidiol
(-)-7-Nor-7-carboxy cannabidiol is a phytocannabinoid metabolite. (-)-7-Nor-7-carboxy cannabidiol is a metabolite of Cannabidiol.
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DC76426 BI-113823
BI-113823 is an orally active and selective bradykinin B1 receptor antagonist. BI-113823 can reduce complete Freund's adjuvant.
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DC76425 PD 165929
PD 165929 is a high affinity and competitive non-peptide neuromedin-B (NMB) receptor selective antagonist (Ki: 6.3 nM; IC50: 150 nM for rat NMB receptor).
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DC76424 AMTG-DA1
AMTG-DA1 is a Gastrin-releasing peptide receptor (GRPR) ligand. AMTG-DA1 can be used in the study of cancer.
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DC76423 KR31173
KR31173 is an AT1 antagonist with an IC50 of 3.27  nM. KR31173 can be used as a positron emission tomography (PET) tracer after being labeled with 11C isotope. KR31173 shows promising biodistribution and pharmacological properties in mice. KR31173 selectively binds to organs known to contain a high density of AT1 angiotensin receptors in CD-1 mice.
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