To enhance service speed and avoid tariff delays, we've opened a US warehouse. All US orders ship directly from our US facility.
| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC44119 | Nevirapine-D4 |
Nevirapine-D4 is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM.
More description
|
|
| DC44118 | Reverse transcriptase-IN-1 |
Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 IIIB, E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC50of 13.7 nM against HIV-1 reverse transcriptase enzyme.
More description
|
|
| DC44117 | HCV-IN-31 |
HCV-IN-31 (compound 4) is a HCV inhibitor, with an EC50/EC95 of 15.7 μM for HCV replicon.
More description
|
|
| DC44116 | HBV-IN-4 |
HBV-IN-4, a phthalazinone derivative, is a potent and orally active HBV DNA replication inhibitor with an IC50 of 14 nM. HBV-IN-4 induces the formation of genome-free capsids and has potent anti-HBV potencies.
More description
|
|
| DC44115 | 1-Dodecylimidazole |
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity.
More description
|
|
| DC44109 | Bis-acrylate-PEG5 |
Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44108 | Benzyl-PEG7-t-butyl ester |
Benzyl-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44107 | BET bromodomain inhibitor 1 |
BET bromodomain inhibitor 1 is an orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor with an IC50 of 2.6 nM for BRD4. BET bromodomain inhibitor 1 binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities (Kd values of 1.3 nM, 1.0 nM, 3.0 nM, 1.6 nM, 2.1 nM, respectively). bromodomain inhibitor 1 has anti-cancer activity.
More description
|
|
| DC44105 | UZH1a |
UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1a can be used for epitranscriptomic modulation of cellular processes. UZH1a has antitumor activity. UZH1a also can be used as a chemical probe for studying METTL3.
More description
|
|
| DC44104 | Hydrazide-PEG4-Desthiobiotin |
Hydrazide-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44103 | Benzyl-PEG7-azide |
Benzyl-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44100 | Benzyl-PEG6-azide |
Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44097 | 7-Iodo-7-deaza-2'-deoxyguanosine |
7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions.
More description
|
|
| DC44096 | Benzyl-PEG3-methyl ester |
Benzyl-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44095 | 3-Aminophenol-PEG4-methyl |
3-Aminophenol-PEG4-methyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44094 | 2-Ethyl-6-methylphenol |
2-Ethyl-6-methylphenol, alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol exhibits insecticidal and bactericidal activities.
More description
|
|
| DC44093 | 2,4-Dimethoxybenzyl alcohol |
2,4-Dimethoxybenzyl alcohol, an aromatic alcohol, is a substrate of glucose-methanol-choline (GMC) oxidoreductase. GMC oxidoreductase displays the characteristics of an aryl-alcohol oxidase.
More description
|
|
| DC44092 | Benzyl-PEG2-ethanol |
Benzyl-PEG2-ethanol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44091 | Endo-BCN-Nitrobenzene |
Endo-BCN-Nitrobenzene is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44090 | ddGTP |
ddGTP (2',3'-Dideoxyguanosine 5'-triphosphate) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing.
More description
|
|
| DC44089 | FLT3-IN-4 |
FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia.
More description
|
|
| DC44088 | rel-Zotatifin |
rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex.
More description
|
|
| DC44087 | THP-PEG1-Boc |
THP-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44086 | Boc-C2-NH2 |
Boc-C2-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44085 | Acid-PEG2-ethyl propionate |
Acid-PEG2-ethyl propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44084 | Pyrroline-5-carboxylate |
Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44083 | m-PEG2-O-Ph-NH2 |
m-PEG2-O-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44082 | m-PEG2-O-Ph-3-NH2 |
m-PEG2-O-Ph-3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
More description
|
|
| DC44080 | (E)-3-(4-Methoxyphenyl)acrylic acid |
(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic,, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities.
More description
|
|
| DC44079 | Methyl p-coumarate |
Methyl p-coumarate (Methyl 4-hydroxycinnamate), an esterified derivative of p-Coumaric acid (pCA), is isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate could inhibit the melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also has strong in vitro inhibitory effect on A. alternata and other pathogens.
More description
|
|