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Ethaselen

  Cat. No.:  DC46403  
Chemical Structure
217798-39-5
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More than 5000 active chemicals with high quality for research!
Field of application
Ethaselen (BBSKE) is an orally active, selective thioredoxin reductase (TrxR) inhibitor with IC50s of 0.5 and 0.35 μM for the wild-type human TrxR1 and rat TrxR1, respectively. Ethaselen specifically binds to the unique selenocysteine-cysteine redox pair in the C-terminal active site of mammalian TrxR1. Ethaselen, an organoselenium compound, is a potent antitumor candidate that exerts potent inhibition on non-small cell lung cancer (NSCLC) by targeting TrxR.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 217798-39-5
Chemical Name: Ethaselen
SMILES: O=C1N([Se]C2=CC=CC=C12)CCN3[Se]C4=CC=CC=C4C3=O
Formula: C16H12N2O2Se2
M.Wt: 422.20
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_30266_DC46403_217798-39-5
COA
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Cat. No. Product name Field of application
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