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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC39080 1-Aminobenzotriazole
1-Aminobenzotriazole (ABT, 3-Aminobenzotriazole, 1-Benzotriazolylamine, NSC 114498, NSC 656987) is a nonselective and irreversible inhibitor of cytochrome P450 (CYP) enzymes. 1-Aminobenzotriazole is also a substrate and inhibitor of N-acetyltransferase (NAT).
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DC33598 GSK-805 Featured
GSK805, also known as ROR gamma-t-IN-1, is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA binding.
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DC39055 BIIB068 Featured
BIIB068 is a potent, selective, reversible and orally active BTK inhibitor. BIIB068 demonstrated good kinome selectivity with good overall drug-like properties for oral dosing, was well tolerated across preclinical species at pharmacologically relevant doses with good ADME properties, and achieved >90% inhibition of BTK phosphorylation (pBTK) in humans.
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DC9474 Nelfinavir (Mesylate)
Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection.
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DC25028 AUDA Featured
A potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 18 nM and 69 nM for mouse sEH and human sEH, respectively.
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DC23149 Oseltamivir acid
Oseltamivir acid (GS 4071, Ro 64-0802, Oseltamivir carboxylate) is a potent inhibitor of influenza neuraminidase (NA) with Ki of <1 nM for both A and B strains,showed potent activity against COVID-19(SARS-COV-2).
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DC39019 Y-1 Featured
Compound Y-1 exerts the best inhibition activity (IC50 = 0.21 μM) against NA, which is better than oseltamivir carboxylate (OSC) (IC50 = 3.04 μM) and lead AN-329/ 10738021 (IC50 = 1.92 μM).
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DC22089 Rimeporide (EMD-87580)
Rimeporide (EMD87580) is a potent, selective sodium hydrogen exchanger NHE1 inhibitor, show promise as potential therapeutic agents for the treatment of heart failure..
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DC39013 (R)-Viloxazine Hydrochloride Featured
The (S)-isomer of Viloxazine.
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DC39012 (S)-Viloxazine Hydrochloride Featured
The (S)-isomer of Viloxazine.
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DC37997 Leucyltyrosine
Leucyltyrosine is a peptide.
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DC37860 Small cardioactive peptide A
Small cardioactive peptide A is a neuropeptide that modulates neuromuscular synapsis in Aplysia. It also functions as neural cotransmitter in molluscs and exert a role in both the central and peripheral modulation of the control of feeding behavior.
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DC37850 Tetralysine
Tetralysine is a cationic moietie that may be used in the construction of gene delivery vectors and DNA nanoparticles.
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DC37816 S-Adenosyl-L-homocysteine
S-Adenosylhomocysteine is an amino acid derivative used in several metabolic pathways in most organisms. It is an intermediate in the synthesis of cysteine and adenosine.
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DC37806 L-Saccharopine
L-Saccharopine is a product of breakdown of essential amino acid Lysine. Saccharopine is also part of the α-aminoadipate pathway of fungal lysine biosynthesis.
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DC37791 KKI 5
KKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema. In various cancer cell lines, KKI 5 alters membrane potential and increases intracellular Ca2+, inhibiting cell proliferation.
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DC37755 Carvyl propioate
Carvyl propioate is a Skin / Eye Irritant.
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DC37723 Pidolic acid
Pidolic acid is a cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism.
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DC37359 Dichlofenthion
Dichlofenthion is a phosphorothioate which is primarily used as a pesticide and nematicide.
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DC37263 4-Hydroxymetanilic acid
4-Hydroxymetanilic acid is a biochemical.
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DC37141 4-Acetylaniline
4-Acetylaniline is a biochemical.
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DC37111 4-Chlorobenzenesulfonamide
4-Chlorobenzenesulfonamide is a sulfonamide derivative.
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DC37087 p-tert-Butylphenol
p- tert- Butylphenol is a chemical compound from the group of phenols .
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DC36832 (+)-Gallocatechin
(+)-Gallocatechin is a polyphenol and flavonoid that has been isolated from the leaves of tea plants and has diverse biological activities.
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DC36802 Lymecycline
Lymecycline is a semisynthetic antibiotic related to TETRACYCLINE.
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DC36748 Benoxacor
Benoxacor is an inert agricultural chemical that acts as an herbicide safener to protect crops from herbicide toxicity.
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DC36550 Dicloran
Dicloran is a biochemical.
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DC36492 Anpirtoline hydrochloride
Anpirtoline HCl is highly potent 5-HT1B receptor agonist which decreases central serotonin synthesis and attenuates aggressive behavior in vivo. Anpirtoline HCl also acts as an antagonist at 5-HT3 receptors and is brain penetrant. Anpirtoline is a receptor agonist with antinociceptive/antidepressant-like actions in rodents.
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DC36455 24-norUrsodeoxycholic acid
Norucholic acid is a Ursodeoxycholic Acid (U850000) derivative. It is superior to Ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
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DC36261 Cerebroside C
Cerebroside C is a fungal metabolite and glycosphingolipid that induces production of the phytoalexin momilactone A when applied to wounded rice leaves, indicating that cerebroside C is an elicitor of the hypersensitive response in rice. Cerebroside C increases germination rate and reduces germination time in wheat seeds in a concentration-dependent manner at 4°C. It also increases root length, fresh weight, and dry weight of wheat seedlings when used at a concentration of 20 μg/ml at 4°C, indicating increased chilling tolerance.
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