Aplaviroc, also known as AK-602; GW-873140; GW873140A; ONO-4128, is a CCR5 entry inhibitor for the potential treatment of HIV infection. Aplaviroc (GW873140) binds specifically to human cellular CC chemokine receptor 5 (CCR5) and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.

Rhosin (G04) is a potent, specific RhoA subfamily Rho GTPases inhibitor that specifically binds to RhoA to inhibit GEF reaction of RhoA with Kd of 0.4 uM, does not interact with Cdc42 or Rac1, nor the LARG.

Fantofarone is a calcium channel blocker.

FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

Fimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure.

Flavoxate Hydrochloride(DW-61 Hydrochloride) is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic.

FLI-06 is a novel potent and selective small molecule intercepting Notch signaling and the early secretory pathway (EC50 ~2.3 μM).

Pemetrexed Disodium Hemipentahydrate

Fluticasone furoate is a synthetic trifluorinated corticosteroid with potent anti-inflammatory activity.

FMF-04-159-2 is a covalent CDK14 inhibitor. FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively.

For the detailed information of NI-(S)-BPB-GLY, the solubility of NI-(S)-BPB-GLY in water, the solubility of NI-(S)-BPB-GLY in DMSO, the solubility of NI-(S)-BPB-GLY in PBS buffer, the animal experiment (test) of NI-(S)-BPB-GLY, the cell expriment (test) of NI-(S)-BPB-GLY, the in vivo, in vitro and clinical trial test of NI-(S)-BPB-GLY, the EC50, IC50,and Affinity of NI-(S)-BPB-GLY, Please contact DC Chemicals..

For the detailed information of praeruptorin B, the solubility of praeruptorin B in water, the solubility of praeruptorin B in DMSO, the solubility of praeruptorin B in PBS buffer, the animal experiment（test） (test) of praeruptorin B, the cell expriment (test) of praeruptorin B, the in vivo, in vitro and clinical trial test of praeruptorin B, the EC50, IC50,and Affinity of praeruptorin B,, please contact DC Chemicals..

HIV-1 integrase inhibitor 8 is a HIV-1 integrase inhibitor, compound 8[1].

FPH1 (BRD-6125) is a small molecule, which promotes expansion of iPS-derived hepatocytes.

Fraxinellone is a selective blocker of voltage-dependent Ca2+ channel, which possesses antimicrobial, anti-inflammatory, neuroprotective and vasorelaxing activities.

FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme.

Fulacimstat(BAY 1142524) is a small molecule chymase inhibitor.

Fumalic acid (Ferulic acid)

GCN2-IN-1 is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with IC50s of <0.3 μM in the enzyme and cell assay.

GDP366, a dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells.

Genistein is a highly specific inhibitor of protein tyrosine kinase (PTK).

Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM.

GIBH-130 is a novel inhibitor of neuroinflammation effective in Alzheimer’s disease models.

GJ103 is an active analog of the read-through compound GJ072.

AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM, shows no activity against the NTR1 receptor as well as a panel of targets known to bind acidic molecules (δ-Opioid, GPR40, PPARδ, EP1, Angiotensin AT1, Endothelin

Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM).

LY2584702 is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM.

Fasentin is a novel inhibitor of glucose uptake (GLUT) that sensitizes cancer cells to FAS-induced cell death, preferentially inhibits GLUT4 (IC50=68 uM) over GLUT1.

Ombrabulin (AVE8062) hydrochloride is a synthetic derivative of CA-4-P, which inhibits growth in a large number of drug-resistant animal tumors and carcinogen-induced tumors.

Nalfurafine (TRK-820, TRK820) is potent, selective agonist of kappa-opioid receptor with Ki of 3.5 nM, 15-fold less potent for μOR and little affinity for δOR (Ki=53 and 1,200 nM, respectively).