N-Mal-N-bis(PEG4-NHS ester) is a branched PEG derivative with a terminal maleimide group and two terminal NHS esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The NHS esters can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Mal-amido-PEG2-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

m-PEG10-azide is a PEG derivative containing an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.

Mal-PEG4-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

t-Boc-N-Amido-PEG7-propargyl is a PEG derivative containing a propargyl group and Boc-protected amino group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a branched alkyne PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG Linker.

N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a branched alkyne PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

Propargyl-PEG10-amine

N-(Azido-PEG4)-N-Boc-PEG4-t-butyl ester is a branched PEG derivative with a terminal azide group, Boc protected amine, and a terminal t-butyl ester. The azide group enables PEGylation via Click Chemistry. The protected amine can be deprotected by acidic conditions, and the t-butyl protected carboxyl group can be deprotected under mild acidic conditions.

N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester) is an Aminooxy PEG Linker. Aminooxy-PEG can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage.

N-(Boc-PEG4)-NH-PEG4-t-butyl ester is an Amino PEG Linker. PEG Amines contain an amino group which can react with acids, succinimidyl-active esters, or pentafluorophenyl esters for labeling, chemical modification, surface or particle modifications. Therefore, PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) is a branched PEG derivative with a terminal hydroxy group and two t-butyl esters. The hydroxy group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a branched alkyne PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester is a branched PEG derivative with a terminal azide group, Boc protected amino group, and a terminal NHS ester. The azide group enables PEGylation via Click Chemistry. The protected amine can be deprotected by acidic conditions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

N-(Azido-PEG3)-N-Boc-PEG4-acid is a branched PEG derivative with a terminal azide group, Boc protected amino group, and a terminal carboxylic acids. The azide group enables PEGylation via Click Chemistry. The protected amine can be deprotected by acidic conditions. The terminal carboxylic acid can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester is a branched PEG derivative with a terminal azide group, Boc protected amine, and a terminal t-butyl ester. The azide group enables PEGylation via Click Chemistry. The protected amine can be deprotected by acidic conditions, and the t-butyl protected carboxyl group can be deprotected under mild acidic conditions.

N-(Azido-PEG2)-N-bis(PEG4-t-butyl ester) is a branched PEG derivative with a terminal azide group and two t-butyl esters. The azide group enables PEGylation via Click Chemistry. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.

N-(Azido-PEG3)-N-bis(PEG4-acid) is a branched PEG derivative with two terminal caboxylic acids and a terminal azide group. The azide group enables PEGylation via Click Chemistry. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

N-(Azido-PEG3)-N-Boc-PEG3-acid is a branched PEG derivative with a terminal azido group, Boc protected amino group, and a terminal carboxylic acid. The azide group enables PEGylation via Click Chemistry. The protected amine can be deprotected by acidic conditions. The terminal carboxylic acid can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

t-boc-N-amido-PEG9-azide is a PEG derivative containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

Mal-amido-PEG9-acid is a PEG derivative containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Mal-amido-PEG7-acid is a PEG derivative containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

N-Mal-N-bis(PEG2-acid) is a branched PEG derivative with two terminal carboxylic acids and a maleimide group. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Ald-Ph-PEG3-O-NH-Boc is a PEG Linker.

Azido-PEG3-succinimidyl carbonate is a PEG Linker

Gly-PEG3-amine, TFA salt is an Amino PEG Linker. PEG Amines contain an amino group which can react with acids, succinimidyl-active esters, or pentafluorophenyl esters for labeling, chemical modification, surface or particle modifications.

Boc-Gly-PEG3-endo-BCN is a PEG derivative. PEG Linkers and PEG derivatives may be useful in the development of antibody drug conjugates and drug delivery methods.

Mahanimbine is a major carbazole alkaloid from Murraya koenigii (curry leaves) that may alleviate development of HFD-induced metabolic alterations.