Pimicotinib, also known as ABSK021, is a tyrosine kinase inhibitor and antineoplastic. It is a small molecule CSF-1R inhibitor that is orally available. Pimicotinib has antitumor activity and a solid white to off-white appearance. Its formula is C22H24N6O3 and its CAS number is 2253123-16-7.

Rezatapopt, also known as PC14586, is p53 Y220C reactivator that binds selectively to p53 Y220C mutant protein and restores the p53 wildtype conformation and transcriptional activity, resulting in potent preclinical antitumor activity. PC14586 was structurally designed to bind tightly to a crevice within the mutant protein (KD~2.5 nM). PC14586 was shown to stabilize the Y220C mutant in the wild type conformation, resulting in reactivation of p53 transcriptional activity and subsequent expression of its target proteins (e.g. p21, MDM2, Bax, PUMA). The reactivation of p53 function is highly selective to Y220C mutant cells and results in arrest of the cell cycle in vitro (IC50 ~0.230-1.8 μM). In nude mice bearing Y220C mutant NUGC3 gastric cancer xenograft tumors, oral administration of PC14586 results in a dose responsive anti-tumor effect. In human xenografts, PC14586 was shown to convert Y220C mutant to the wildtype conformation, resulting in activation of p53 transcription.

MAO-B-IN-19 is a selective MAO-B inhibitor with an IC50 of 0.67 μM.

GPAT-IN-1 is a glycerol-3-phosphate acyltransferase (GPAT) inhibitor

Carfecillin Sodium, also known as Carbenicillin Phenyl Sodium and BRL-3475, is the phenyl ester of Carbenicillin that, upon oral administration, is broken down in the intestinal mucosa to the active antibacterial. It is used for urinary tract infections.

Bifemelane, also known as MCI-2016, is Antidepressant MAO inhibitor used to treat cerebral infarction and Alzheimer's disease. At concentrations of 10 - 30 microM, Bifemelane induced a slow onset and small increase in the [Ca2+]i, while at higher concentrations (100 - 300 microM), it induced a rapid transient increase in the [Ca2+]i during administration and a second large increase was seen during drug washout.

WAY-615145 is a glucokinase activator.

RIG012 is a potent RIG-I inhibitor. It inhibits IFN-β and ISG hRsad2 expression.

CZL55 is a caspase-1 inhibitor. CZL55 can be used for the research of febrile seizures (FS)

Z26395438 (compound 1) is a potent Sirtuin-1 inhibitor.

RS5517 is a specific PDZ1-domain antagonist of NHERF1.

LW3 is a potent antifungal agent.

MSNBA is a specific inhibitor of GLUT5 fructose transport in proteoliposomes.

Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction.

Valomaciclovir stearate (A-174606.0; ABT-606; EPB-348; MIV-606; RP-606) is a DNA polymerase inhibitor potentially for treatment of acute herpes zoster and EB virus infection. Valomaciclovir stearate is an orally available and a prodrug of Valomaciclovir with broad-spectrum antiviral activity against a variety of important herpesviruses, including Epstein-Barr virus, or EBV (the first virus to be directly associated with human cancer), varicella zoster virus, or herpes zoster (cause of shingles), and herpes simplex virus 1 and 2.

Bisaramil, also known as NK-1556 and RGH-2957, is a calcium channel antagonist and sodium channel antagonist potentially for the treatment of arrhythmia.

BIT-225 is a NCp7 zinc finger inhibitor potentially for the treatment of HCV infection and HIV infection. BIT225 inhibits HIV-1 replication in myeloid dendritic cells. BIT225, inhibits bovine viral diarrhea virus in vitro and shows synergism with recombinant interferon-alpha-2b and nucleoside analogues. BIT225 against HIV-1 release from human macrophages.

WAY-301464 is a Pim-1 inhibitor.

WAY-354896 is a Dual activator of Protein Kinase R (PKR) and Protein Kinase R-Like Kinase (PERK).

WAY-278705 is a phosphoinositide 3-kinase (PI3 kinase) modulator.

GW0193 is also named as 7-(2-(oxiran-2-yl)ethoxy)-2H-chromen-2-one. It is a coumarin derivative.

HFY-4A is a HDAC inhibitor. HFY-4A inhibits breast cancer cell proliferation, migration, and invasion, and induces cell apoptosis.

Z16078526 induces endogenous Ucp1 expression, promotes p38 MAPK phosphorylation and lipolysis.

PRE 084 is a high affinity selective sigma 1 agonist.

ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist. ZK 756326 inhibited the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM. ZK 756326 was a full agonist of CCR8, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1.

WJ-39 is an orally active aldose reductase (AR) inhibitor.

DOTA is an azamacrocyle in which four nitrogen atoms at positions 1, 4, 7 and 10 of a twelve-membered ring are each substituted with a carboxymethyl group. It has a role as a chelator and a copper chelator. It derives from a hydride of a 1,4,7,10-tetraazacyclododecane. It is a a metal chelate in use in medical diagnostics.

DOTA-LM3 is a somatostatin receptor ( SSTR ) antagonist.

NOTA-JR-11 is a somatostatin receptor (SSTR) antagonist.

NOTA-cyclic RGDyK is a ligand to bind 68Ga for molecular imaging of αvβ3 integrin overexpressing tumor.