NSC-207895 is an inhibitor of the p53-binding protein MDMX. NSC 207895 decreases the expression and protein levels of MDMX and increases the expression of the p53 target gene CDKN1 (p21). It also increases the expression of the pro-apoptotic genes PUMA, Bax, and PIG3. NSC 207895 induces apoptosis and decreases cell viability in MCF-7 cells in a p53-dependent manner. It also induces p53-independent apoptosis in wild-type, mutated, and truncated p53 Ewing sarcoma cell lines selectively over wild-type and p53-null osteosarcoma cells

Acetamide, N-(2-ethoxyphenyl)- is a biochemical.

Azido-PEG4-t-butyl ester is a PEG derivative containing an azide group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

SPDP-PEG4-acid is a PEG Linker.

Amino-PEG4-t-butyl ester is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

Tos-PEG5-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Leucovorin is the active metabolite of folic acid. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid.

Averantin is an Aflatoxin B(1) precursor.

Apomorphine hydrochloride is a Dopamine (D1 and D2) receptor agonist which may be effective in the treatment of Parkinson's disease.

O-Methylsalicylic acid is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ)

Proctolin modulates interneuronal and neuromuscular synaptic transmission in a wide variety of arthropods.

Acequinocyl is a pesticide.

Deacyl acebutolol also known as rac N-Desbutyroyl Acebutolol (Acebutolol EP Impurity D), it is the major metabolite of Acebutolol (sc-217555).

Acridone is an organic compound based on the acridine skeleton, with a carbonyl group at the 9 position. It may be synthesized by the self-condensation of N-phenylanthranilic acid. acridone could induce cell apoptosis, inhibited ABCG2 (ATP-binding cassette sub-family G member 2) protein and adjusted hormone level.

ROPA, also known as Resiniferonol 9,13,14-ortho-phenylacetate, is a potent PKCalpha and PKCgamma activator that promotes tumor growth through PKC-activation.

Metalaxyl is an acylalanine fungicide with systemic function. Its chemical name is methyl N-(methoxyacetyl)-N-(2,6-xylyl)-DL-alaninate. It can be used to control Pythium in a number of vegetable crops, and Phytophthora in peas. Metalaxyl-M or Ridomil Gold are trade names for the optically pure (-) / D / R active stereoisomer, which is also known as Mefenoxam.

Gentamicin X2 Sulfate is a potent premature stop codon readthrough molecule and the common precursor of the gentamicin C antibiotic complex.

Iodoalphionic acid is a biochemical.

Carazolol is a beta1/beta2 adrenoceptor antagonist of high potency used in the treatment of hypertension. Its affinity for the beta 3-adrenoceptor was determined in Chinese hamster ovary cells transfected with the gene of the human or the murine beta 3-adrenoceptor. Carazolol is recognized with a nanomolar affinity, which positions it among the best ligands for beta 3-adrenoceptors.

Etoperidone hydrochloride is an antidepressant.

DSP Crosslinker, also known as DTSSP Crosslinker, is a homobifunctional and cleavable crosslinker that is cell membrane permeable. DSP crosslinker has amine-reactive N-hydroxysuccinimide (NHS) esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm, and DSP cross links occur via these NHS esters.

Heptelidic acid is an esquiterpene lactone produced by the fungus T. koningii with antibiotic activity against anaerobic bacteria such as Bacteroides. It acts as an irreversible inhibitor of GAPDH that binds to the cysteine-149 residue at the active site of the enzyme.

Benzyl-PEG6-alcohol is a Benzyl PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

Sulfaguanidine is a sulfanilamide antimicrobial agent that is used to treat enteric infections. It functions by blocking the production of folic acid, to act as an antibiotic. It is active against Gram positive bacteria and Gram negative bacteria.

Timiperone is butyrophenone derivative which has neuroleptic activity. Used as an antipsychotic.

Furalaxyl is an acylamino chiral fungicide.

Bismuth subcitrate contains tripotassium di-citratobismuthate used in gastric & duodenal ulcer therapy. Bismuth subcitrate potassium is a bismuth salt used in combination with antibiotics and a proton pump inhibitor for the treatment of Helicobacter pylori infections.

Bromo-PEG3-alcohol is a PEG derivative containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Bromo-PEG2-alcohol is a PEG derivative containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Chlortetracycline is a broad-spectrum antibiotic tetracycline with a 7-chloro substitution. It inhibits growth of both Gram-positive and Gram-negative bacteria. It acts by inhibiting protein synthesis.