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Cat. No. Product Name Field of Application Chemical Structure
DC35591 m-PEG5-2-methylacrylate
m-PEG5-2-methylacrylate is a PEG derivative. PEG Linkers and derivatives may be useful in the development of antibody drug conjugates.
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DC37980 Lecanoric acid
Lecanoric acid is a naturally occurring depside polyphenol isolated from a variety of lichens. It is a potent antioxidant, surpassing ascorbic acid in a 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging assay (IC50s = 424.51 and 6.42 μg/ml for lecanoric and ascorbic acid, respectively). Lecanoric acid has antibacterial and antifungal activities with minimum inhibitory concentrations ranging from 0.5 to 1 mg/ml for a panel of fifteen microorganisms. In a cell viability assay, lecanoric acid exhibits antiproliferative activity against HeLa cells (IC50 = 123.97 μg/ml). Lecanoric acid also exhibits antidiabetic and hypolipidemic properties.
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DC38042 DU-176
Edoxaban (INN, codenamed DU-176b, trade name Lixiana) is a potent, selective factor Xa inhibitor, which has good oral bioavailability. Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is being developed by Daiichi Sankyo. It was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower-limb orthopedic surgery. It was also approved by the FDA in January 2015 for the prevention of stroke and non?–central-nervous-system systemic embolism.
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DC35481 Pentaethylene glycol
Pentaethylene glycol is a PEG Linker. PEG Linkers may be useful int he development of antibody drug conjugates.
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DC34916 Amino-PEG11-amine
Amino-PEG11-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates or drug delivery methods.
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DC34370 MMPIP Hydrochloride
MMPIP HCl is an allosteric mGlu7-selective receptor antagonist.
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DC33882 FAM alkyne, 6-isomer
Alkyne derivative of FAM (fluorescein) fluorophore for Click Chemistry. Pure (97+%) single 6-isomer. Fluorescein is a bright fluorophore which is compatible with a number of different fluorescent instruments.
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DC34769 2-Iminothiolane
2-Iminothiolane HCl, or Traut's Reagent,is commonly used to convert primary amines into sulfhydryl groups in a one-step process is called thiolation. It is a useful RNA-protein crosslinking reagent and an effective thiolation reagent for polysaccharides.
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DC36926 Evoxanthine
Evoxanthine is an alkaloid that has been found in O. renieri and has antimalarial and anticancer activities.
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DC35871 m-PEG3-succinimidyl carbonate
m-PEG3-succinimidyl carbonate is a PEG Linker.
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DC34104 Isotetrandrine
Isotetrandrine is a cell-permeable PLA2 inhibitor. It can block NMO-IgG binding to AQP4 without affecting the expression and function of AQP4. It can also inhibit NMO-IgG binding to astrocyte AQP4 in NMO patient sera and block NMO-IgG-dependent complement-mediated cytotoxicity.
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DC38066 Boldine
Boldine is an alkaloid of the aporphine class that can be found in the boldo tree and in Lindera aggregata. Boldine has antioxidant activity that effectively protects against free radical induced lipid peroxidation or enzyme inactivation. In addition, it has alpha-adrenergic antagonist activities in vascular tissue, and it has also been reported to have hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.
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DC34177 Glaucine
Glaucine is an inhibitor of TNF-alpha and IL-6 production induced by Toll-like receptor (TLR) ligands.
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DC35177 Boc-NH-PEG2-NH-Boc
Boc-NH-PEG2-NH-Boc is a PEG derivative. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC37662 Longifolene
Longifolene is the common (or trivial) chemical name of a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins. The name is derived from that of a pine species from which the compound was isolated, Pinus longifolia (obsolete name for Pinus roxburghii Sarg.) Chemically, longifolene is a tricyclic sesquiterpene. This molecule is chiral, and the enantiomer commonly found in pines and other higher plants exhibits a positive optical rotation of +42.73°. The other enantiomer (optical rotation ?42.73°) is found in small amounts in certain fungi and liverworts. Longifolene is used in organic synthesis for the preparation of dilongifolylborane, a chiral hydroborating agent.
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DC34280 2-MeS-ADP
2-MeS-ADP is a purinergic agonist. It acts by displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors and inhibiting cAMP accumulation.
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DC34566 Galnon
Galnon is a selective, non-peptide agonist at the galanin receptors GALR.
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DC36419 Iloperidone metabolite P95
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone. It binds to the serotonin (5-HT) receptor subtype 5-HT2A and α1-, α2B-, and α2C-adrenergic receptors but does not cross the blood-brain barrier.
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DC36821 KT 1
KT 1 decreased aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increased aortic blood flow, vertebral blood flow, coronary blood flow, peak positive left ventricular dP/dt and heart rate in anesthetized open-chest dogs.
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DC38040 Glycolithocholic acid
Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.
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DC34480 Cerebrosterol
Cerebrosterol is a major brain metabolite of cholesterol.
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DC34517 Chalinasterol
24-Methylenecholesterol is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.
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DC34914 Amino-PEG9-amine
Amino-PEG9-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC37296 Dichloramine-T
Tosylchloramide or N-chloro tosylamide, sodium salt, sold as chloramine-T, is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant. It is a white powder that gives unstable solutions with water.
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DC35613 Hexane-1
Hexane-1,6-diyldiphosphonic acid is a non-PEG crosslinker.
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DC37193 Boswellic acid
Boswellic acid promotes induction of apoptosis, cell cycle arrest, cell migration inhibition and inhibition of PI3K/AKT signalling pathway.
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DC36503 Calcium carbonate
Calcium carbonate is a naturally occurring compound used as a calcium supplement and antacid. Also used in laboratories as a buffer. Shown in renal-disease patients with hyperphosphatemia to contain phosphate binding power, but may result in hypercalcaemia or alkalosis. Other experiments have successfully utilized calcium carbonate as a calcium control in comparison studies.
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DC37767 Felinine
Felinine is a sulfur-containing amino acid; a major component in the urine of domestic cat.
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DC34249 GW438014A
GW438014A is a selective NPY-Y5 receptor antagonist.
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DC37614 C.I. Acid Green 3
C.I. Acid Green 3 is a dull dark green powder. Used as a dye for silk or wool and biological stains.
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