cis-Clopidogrel-MP Derivative (Clopidogrel-MP-AM) is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite. Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor.

Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively.

Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity.

O-Desmethyl mycophenolic acid methyl ester is an intermediate in the synthesis of Mycophenolic acid.

Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate (Win35833) is a potent peroxisome proliferator, increases the phosphorylation level of the PPARalpha.

Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is an impurity of Rivastigmine. Rivastigmine is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM, 4.15 μM, respectively.

Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study.

Trityl olmesartan medoxomil impurity III is an impurity of Trityl olmesartan medoxomil. Trityl olmesartan medoxomil is an intermediate of Olmesartan medoxomil.

Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM.

Seco Rapamycin ethyl ester is an open-ring metabolite of Rapamycin derivative. Seco-rapamycin is reported not to affect the mTOR function.

PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines.

PROTAC BRD4 Degrader-5-CO-PEG3-N3 (Compound 2) is a PROTAC-linker Conjugate for PAC, comprises the BRD4 degrader GNE-987 and PEG-based linker.

2-Nitrobenzaldehyde semicarbazone 13C,15N2 is used for analysis of semicarbazide in the LC-MS/MS method.

Geldanamycin-FITC, a Geldanamycin fluorescent probe, can be used in a fluorescence polarization assay for HSP90 inhibitors. Geldanamycin-FITC also can be used for detection of cell surface HSP90.

2-Aminoflubendazole is the metabolite of Benzimidazoles. Benzimidazoles (BZ) are a class of drugs with activities against fungi, protozoa, and helminthes.

N- N-hexanoyl-L-Homoserine lactone regulates virulence in general and in cystic fibrosis, prevents infection, reduces slime and biofilm in commercial agriculture and aquaculture industries, prevents food spoilage, and septicemia in fish.

N-Tetradecanoyl-L-homoserine lactone is a major chemical modulators of within and between cell communication and regulation. N-Tetradecanoyl-L-homoserine lactone can be used for the study of quorum sensing in vitro.

N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule.

(±)-2,3-Dibromosuccinic acid is the key intermediate in the synthesis of dicarboxylic acid derivatives.

β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol.

Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di-(2-ethylhexyl) phthalate (DEHP). Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking.

(Rac)-Mono(3,5,5-trimethylhexyl) phthalate is a important metabolite of commonly used phthalate plasticizers. (Rac)-Mono(3,5,5-trimethylhexyl) phthalate has immuno-suppressive effect.

Monoethyl phthalate is a phthalate metabolite, acts as a urinary biomarker of phthalates exposure indicating the risks of thyroid cancer and benign nodule.

Bromoiodoacetamide is a kind of iodinated haloacetamides (I-HAcAms), with cytotoxicity. Bromoiodoacetamide induces cytotoxicity by via reactive oxygen species (ROS) accumulation and apoptosis in HepG-2 cells.

Diiodoacetamide, a iodo-haloacetamide, is a disinfection by-product (DBP) in drinking water.

2,2-Dibromoacetamide is a class of disinfection by-product (DBP) in drinking water.

Dibromochloroacetamide is one of haloacetamides, which are the drinking water disinfection byproducts (DBPs).

Diiodoacetic acid is a disinfection by-product (DBP) formed during water disinfection.

Chloroiodoacetic acid exists in the water disinfected with chlorine/hypochlorite.

Bromoiodoacetic acid, one of iodinated haloacids, is a disinfection byproduct (DBP) at in finished drinking waters.