A selective inhibitor of B-RAF protein kinase carrying V600E mutation

Less active enantiomer of LGH447 (AOB37522)

Novel Inhibitor of Human Cytomegalovirus

Selective NPY-Y2 Receptor Antagonist

Novel G6PD inhibitor

Novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC anchorage-dependent and anchorage-independent growth,

HIV inhibitor, showing selective activity against human RNaseH2

Novel potent and selective Plk1 inhibitor

Novel potent inhibitor of human cathepsin L

A potent and specific inhibitor of the cerebroside synthase

Modulator of Lipid Storage

Less active enantiomer of ML206 (AOB1395), acting as a modulator of lipid storage

Control molecule for HyT36 (AOB4848) which is a hydrophobic inducer of the degradation of stabilized proteins

Novel Pim-2 inhibitor, inducing apoptosis and autophagic cell death in triple-negative human breast cancer

PKC activator, stimulating PKC mediated myosin light chain phosphorylation without activating MLC kinase

Antiepileptic anticonvulsant, significantly attenuating after discharge durations and the severity of the accompanying convulsive responses

Novel selective PPARalpha modulator (SPPARMalpha), improving dyslipidemia, enhancing reverse cholesterol transport and decreasing inflammation and atherosclerosis

Selective Phospholipase A2 Inhibitor

Novel autophagy inhibitor, selectively targeting cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A), and directly competing with cholesterol binding to the GRAMD1A StART domain

Novel focal adhesion kinase (FAK) inhibitor

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) is an abundant LPA species with high biological activity due to its strong affinity for the LPA receptors. 1-Oleoyl lysophosphatidic acid is commonly used in most laboratories as a reagent for LPA receptor activation. 1-Oleoyl lysophosphatidic acid increases SRE-drivenβ-galactosidase activity.

CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology.

(S,R,S)-AHPC-PEG5-Boc is a E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for Cdc20 degrader CP5V.

Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology.

Fmoc-NH-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions.

AMPK activator 4 is a potent AMPK activator without inhibition of mitochondrial complex I. AMPK activator 4 selectively activates AMPK in the muscle tissues. AMPK activator 4 dose-dependently improves glucose tolerance in normal mice, and significantly lowers fasting blood glucose level and ameliorates insulin resistance in db/db diabetic mice. Anti-hyperglycemic effect.

[Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology.

THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.