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Cat. No. Product Name Field of Application Chemical Structure
DC10064 GSK-F1 Featured
GSK-F1 is a potent inhibitor of PI4KA.
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DC23895 AY-9944 Featured
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol.
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DC39202 NMDAR/TRPM4 inhibitor 19 (Compound 19) Featured
NMDAR/TRPM4 inhibitor 9 (Compound 9) is a neuroprotective NMDAR-TRPM4 interaction interface inhibitor but spare the critical healthy NMDAR function.
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DC10924 BMS986202 Featured
BMS-986202 is a clinical Tyk2 inhibitor that binds to Tyk2 JH2 with IC50 of 0.19 nM and shows remarkably selectivity over other kinases including Jak family members.
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DC22191 PBT434 Featured
PBT434 is a novel quinazolinone compound with effect of lowering cellular iron levels, prevents iron mediated neurodegeneration and α-synuclein toxicity in multiple models of Parkinson disease; inhibits iron-mediated redox activity and iron-mediated aggregation of α-synuclein, a protein that aggregates in the neuropathology; prevents loss of substantia nigra pars compacta neurons (SNpc), lowers nigral α-synuclein accumulation, and rescues motor performance in mice model of PD.
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DC40721 GRP-60367 hydrochloride Featured
GRP-60367 hydrochloride is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains. GRP-60367 hydrochloride specifically targets the RABV G protein.
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DC42262 D-Lysine monohydrochloride
D-Lysine monohydrochloride is an Lysine stereoisomer which can be used as a component of surfactants.
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DC42261 2,6-Dibromophenol
2,6-Dibromophenol is an endogenous metabolite.
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DC42260 3-(1-Cyanoethyl)benzoic acid
3-(1-Cyanoethyl)benzoic acid (DF2107Y) is a benzoic acid that can be used to screen cobalt containing nitrile hydratases (NHases).
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DC42259 Hydroxyacetone
Hydroxyacetone is an endogenous metabolite.
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DC42258 Dimethyl sulfone
Dimethyl sulfone is an endogenous metabolite.
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DC42257 Diphenyl disulfide
Diphenyl disulfide is an endogenous metabolite.
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DC42256 Monomethyl phthalate
Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule.
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DC42255 Methoxyacetic acid
Methoxyacetic acid is an endogenous metabolite.
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DC42254 3,4-Dimethoxyphenethylamine
3,4-Dimethoxyphenethylamine is an endogenous metabolite.
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DC42253 4-Pentenoic acid
4-Pentenoic acid is an endogenous metabolite.
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DC42252 1,4-Dichlorobenzene
1,4-Dichlorobenzene is used as an intermediate product in the manufacture of pigments, pesticides and disinfectants. 1,4-Dichlorobenzene is also employed as a moth control agent.
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DC42251 Semicarbazide hydrochloride
Semicarbazide hydrochloride, a derivative of urea, possesses antiviral, antiinfective and antineoplastic through binding to copper or iron in cells.
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DC42250 1-Aminohydantoin hydrochloride
1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection.
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DC42249 D-Tyrosine
D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth.
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DC42248 2-Methylbenzaldehyde
2-Methylbenzaldehyde is an endogenous metabolite.
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DC42247 D-Leucine
D-Leucine is a more potent anti-seizure agent than L-leucine. D-leucine potently terminates seizures even after the onset of seizure activity. D-leucine, but not L-leucine, reduces long-term potentiation but had no effect on basal synaptic transmission in vitro.
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DC42246 1-Dodecanol
1-Dodecanol is an endogenous metabolite.
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DC42245 Phenoxyacetic acid
Phenoxyacetic acid is an endogenous metabolite.
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DC42244 3-Indoleacetonitrile
3-Indoleacetonitrile is an endogenous metabolite.
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DC42243 2,6-Dihydroxyacetophenone
2,6-Dihydroxyacetophenone is an endogenous metabolite.
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DC42242 4,4-Dimethoxy-2-butanone
4,4-Dimethoxy-2-butanone is an endogenous metabolite.
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DC42240 p-Dimethylaminobenzaldehyde
L-Prolylglycine is an endogenous metabolite.
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DC42239 L-Prolylglycine
Chlorobutanol hemihydrate is a pharmaceutical preservative with sedative-hypnotic actions. Chlorobutanol hemihydrate is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol hemihydrate is widely used in food and cosmetic industry.
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DC42238 Chlorobutanol hemihydrate
Thalidomide 5-fluoride is Thalidomide-based cereblon ligand?that incorporates to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
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