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Cat. No. Product Name Field of Application Chemical Structure
DC34838 Propargyl-PEG4-methane
Propargyl-PEG4-methane is a PEG derivative containing a propargyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34826 Propargyl-PEG3-Ms
Propargyl-PEG3-Ms is a PEG derivative containing a propargyl group and a Ms group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34807 Propargyl-PEG12-amine
Propargyl-PEG12-amine is a PEG derivative containing a propargyl group and an amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers are useful in the development of antibody drug conjugates.
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DC34802 Propargyl-PEG3-amine
Propargyl-PEG3-amine is a PEG derivative containing a propargyl group and an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers are useful in the development of antibody drug conjugates (ADCs).
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DC34799 Propargyl-PEG7-alcohol
Propargyl-PEG7-alcohol is a PEG derivative containing a hydroxyl group and a propargyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC34794 Propargyl-PEG4-CH2CO2tBu
Propargyl-PEG4-CH2CO2tBu is a PEG derivative containing a propargyl group and t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC34766 Iodoacetyl-LC-Biotin
Iodoacetyl-LC-Biotin, or N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediamine, reacts with sulfhydryl groups to form stable thioether linkages.
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DC34743 Sulfo-SMCC Crosslinker sodium salt
Sulfo-SMCC Crosslinker, or Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a water soluble, heterobifunctional crosslinker. The non-membrane piercing Sulfo-SMCC protein crosslinking reagent can conjugate extracellular proteins. Sulfo-SMCC crosslinker has an 8.3 angstrom, non-cleavable spacer arm.
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DC34741 Sulfo-MBS Crosslinker
Sulfo-MBS Crosslinker, also known as m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester, is a non-cleavable, water soluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody.
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DC34725 C.I. Azoic Coupling Component 12
C.I. 37550 is a fluorescent indicator.
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DC34724 Cibanaphthol AG
C.I. Azoic Coupling Component 5 is a fluorescent indicator.
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DC34699 Toremifene
Toremifene is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. It is antagonistic on mammary and uterine tissue. Licensed in the United States under the brand name Fareston, toremifene is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.
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DC34678 lambda-Cyhalothrin
lambda-Cyhalothrin is an insecticide and pesticide that has adverse effects on rats as well, including neurotoxic and hepatopancreatic effects.
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DC34615 Epiberberine Chloride
Epiberberine Chloride is a natural anticancer agent which stabilizes telomeric G4s and inhibits telomerase, specifically recognizing the hybrid-2 telomeric G4 predominant in physiologically relevant K+ solution and converts other telomeric G4 forms to hybrid-2.
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DC34579 S1-QEL
S1QEL is a suppressor of mitochondrial respiratory complex I site IQ electron leak which suppresses superoxide and/or H2O2 production without altering oxidative phosphorylation.
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DC34577 Tuftsin
Tuftsin is a self-immunomodulatory molecule produced by the spleen by enzymatic cleavage of a leukophilic gamma-globulin which stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
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DC34555 Fluvastatin Methyl Ester
Fluvastatin Methyl Ester is a precursor for Fluvastatin, which is a blocker of the liver enzyme HMG-CoA reductase.
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DC34545 Momordicin I
Momordicine I is a secondary metabolite from bitter melon (Momordica charantia L.) which significantly inhibits Spodoptera litura ovary cell line (SL-1 cell) proliferation.
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DC34513 AV45
Flobetapir is a blood-brain barrier crossing ligand of amyloid protein deposits in the brain.
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DC34495 3-O-Methyl-N-acetyl-D-glucosamine
NAGKi is an inhibitor of N-acetylglucosamine kinase (NAGK) and N-acetylmannosamine kinase (NAMK).
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DC34492 NPD8716
NPD8716 is a hepatitis B/D virus entry inhibitor, targeting sodium taurocholate cotransporting polypeptide (NTCP).
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DC34477 Imidafenacin hydrochloride
Imidafenacin HCl is a potent antimuscarinic agent, exhibiting selectivity toward muscarinic M3 receptors.
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DC34456 Neurodazine
Neurodazine is a neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons.
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DC34444 Clofilium Tosylate
Clofilium Tosylate is a K+ channel blocker, cardiac depressant, and anti-arrhythmic agent.
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DC34425 S3QEL-2
S3QEL-2 is a modulator of the retrograde signaling. It acts by strongly mitigating the oxidative stress-induced apoptosis that limits the yield of functional ?-cells from intact islets.
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DC34420 PQ1 Succinate
PQ1 Succinate is a gap junction enhancer. It acts by restoring GJIC and increasing connexin expression in breast cancer cell lines while not affecting normal mammary cells.
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DC34358 Rhodblock 6
Rhodblock 6 is an inhibitor of the Rho pathway. It acts by specifically abrogating Rho kinase activity.
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DC34353 JMC-4
JMC-4 is a 5-LOX inhibitor.
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DC34315 HNHA
HNHA is a histone deacetylase (HDAC) inhibitor.
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DC34269 TMCB
TMCB is a dual-kinase inhibitor. It acts by inhibiting both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8).
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