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Cat. No. Product Name Field of Application Chemical Structure
DC34780 Propargyl-PEG4-CH2CO2H
Propargyl-PEG4-CH2CO2H is a PEG derivative containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC37020 Acid Violet 6B
Acid Violet 6B is a dye.
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DC37653 Ioxynil
Ioxynil is a herbicide. Ioxynil is a plant protection active substance and a chemical compound from the group of substituted phenols, nitriles and organic iodine compounds .
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DC35737 Azide-PEG4-Tos
Azide-PEG4-Tos is a PEG derivative containing an azide group and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.
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DC36936 Hydroaminacrine
Tacrine hydrochloride is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
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DC36880 Noratropine
Noratropine is a metabolite of Atropine (A794625).
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DC37315 Nicotinic anhydride
Nicotinic anhydride is a biochemical.
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DC35989 Tetrazine-PEG5-NHS ester
Tetrazine-PEG5-NHS ester is a PEG derivative containing a tetrazine group and an NHS ester. The hydrophilic PEG spacer increases water-solubility. It is one of the most reactive tetrazines commercially available. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics compared to methyl substituted tetrazines.
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DC37969 Pantethine
Pantethine is a derivative of vitamin B5.
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DC35517 N-Benzyl-N-bis(PEG3-OH)
N-Benzyl-N-bis(PEG3-OH) is a PEG Linker
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DC34241 TASIN-1 Hydrochloride
TASIN-1 Hydrochloride is a truncated APC selective inhibitor. It acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells.
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DC36257 Z-LRGG-AMC (trifluoroacetate salt)
Z-LRGG-AMC TFA is a fluorogenic substrate for isopeptidase T. Upon enzymatic cleavage by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify isopeptidase T activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
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DC37943 Methomyl
Methomyl is a carbamate insecticide with anticholinesterase activity.
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DC36009 Lipoamido-PEG2-alcohol
Lipoamido-PEG2-alcohol is a PEG Linker.
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DC33755 Octanophenone
Octanophenone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 μm particles columns available for fast UPLC applications. This method is scalable and can be used for isolation impurities in preparative separation.
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DC34538 TerpendoleE
Terpendole E is an atypical L5 site inhibitor.
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DC34753 Sulfo-EGS Crosslinker
Sulfo-EGS Crosslinker, or Ethylene glycol bis(sulfosuccinimidylsuccinate), is a water soluble homobifunctional crosslinker. Sulfo-EGS Crosslinker can be used to label cell surface proteins as the molecule is not cell membrane permeable.
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DC37934 Digoxigenin
Digoxigenin is a cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.
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DC34401 NTE-122
NTE-122 is a potent, selective and competitive inhibitor of Acyl-CoA:cholesterol acyltransferase (ACAT).
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DC35500 Hydroxy-PEG3-acrylate
Hydroxy-PEG3-acrylate is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC37669 JWH-198
JWH 198 is a synthetic cannabinoid (CB) which binds the central CB1 receptor with high affinity (Ki = 10 nM). This aminoalkylindole shares structural features with the antinociceptive CB1 agonists pravadoline and WIN 55,212-2.1 The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.
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DC34918 Azido-PEG2-amine
Azido-PEG2-amine is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34236 p-BrBzGSH(Cp)2
p-BrBzGSH(Cp)2 is an inhibitor of glyoxylase 1 (GLO1). It acts by increasing DNA-AGEs, stimulating RAGE expression, and inhibiting brain tumor growth in orthotopic mouse models.
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DC36467 CI-898 HCl
CI-898 HCl is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). It has enhanced binding to DHFR in the presence of the cofactor NADPH. Cl-898 HCl inhibits cell growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine (6-TG) in mice with advanced stage P338 leukemia.
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DC38060 4-Chloroloratadine
4-Chloroloratadine is an impurity of Loratadine.
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DC33903 Sulfo-Cyanine3 maleimide
Sulfo-Cyanine3 maleimide is a water soluble, thiol reactive dye for the labeling with hydrophilic sulfo-Cyanine3 fluorophore. This is an analog of Cy3? maleimide. This product is recommended for the labeling of antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require use of organic co-solvent.
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DC36256 3-BODIPY-Propanoic Acid
BODIPY 503/512 is a lipophilic, amine-reactive fluorescent probe. It has been used to label oligonucleotide probes and primers for the quantitation of DNA and RNA by PCR and to monitor the uptake and trafficking of BODIPY-labeled proteins and other compounds within cells by fluorescence microscopy. BODIPY 503/512 has also been used to identify and sort adipocytes from mouse white and brown adipose tissue by flow cytometry. It displays excitation/emission maxima of 503/512 nm, respectively.
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DC35385 Fmoc-N-amido-PEG1-acid
Fmoc-N-amido-PEG1-acid is a PEG derivative containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC35084 UV Cleavable Biotin-PEG2-Azide
UV Cleavable Biotin-PEG2-Azide is PEG derivative containing a biotin group and an azide group. The azide group can react to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC37879 Neotame
Neotame is a white colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in variety of foods. It is manufactured from aspartame and 3,3-dimethylbutyraldehyde in a one-step chemical synthesis process.
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