Selegiline is a selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.

NSC-120011, also known as Tris(benzyloxycarbonyl)arginine, is a bioactive chemical.

Ketopioglitazone is an active metabolite of pioglitazone and is found in human plasma.

Leriglitazone is a peroxisome proliferator activated receptor (PPAR) gamma agonist.

Chlorindanol is a spermaticide.

Propargyl-PEG2-Tos is a PEG derivative containing a tosyl group and a propargyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Biotin-PEG4-alkyne is a PEG derivative containing a biotin group and an alkyne group. The alkyne group can react with azide moiety in Cu(I)-catalyzed Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Sophoridine is an antiviral against Coxsackievirus B3. Sophoridine works by regulating cytokine expression which may represent a potential therapeutic agent for viral myocarditis. Sophoridine also has anti-tumor and anti-inflammatory properties.

m-PEG4-(CH2)3-alcohol is a PEG derivative containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Fluorescein-PEG4-azide is a heterofunctional fluorescent PEG derivative containing an azide group, which enables Click Chemistry. The hydrophilic PEG spacer arm increases solubility in aqueous media. The FITC group (Fluorescein) can be easily traced from its yellow color and green fluorescence.

MNF, also known as 3,4-MNF, is an antagonist of the aryl hydrocarbon receptor (AhR). MNF reduces UVR-mediated immunosuppression and induces Tregs in murine contact hypersensitivity (CHS).

Tos-PEG4-acid is a PEG derivative containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

TC-E 5002 is a selective histone demethylase KDM2/7 subfamily inhibitor.

cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone. It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.

GHRP-6 acetate is a synthetic growth hormone (GH) secretagogue and an agonist of the GH secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It inhibits binding of the GHS-R agonist MK-0677 (Ibutamoren) to COS-7 cell membranes expressing human GHS-R type Ia and binding of ghrelin to COS-7 cells expressing human GHS-R. GHRP-6 stimulates intracellular calcium mobilization in BHK cells expressing the human receptor and inositol phosphate production in COS-7 cells expressing the human receptor. It also acts as a negative allosteric modulator of ghrelin signaling. GHRP-6 induces release of GH, but not thyroid-stimulating hormone (TSH), luteinizing hormone (LH), or follicle-stimulating hormone (FSH), in isolated rat pituitary gland. It increases levels of GH, but not TSH, LH, FSH, or prolactin, in rat blood when administered subcutaneously at a dose of 50 μg. GHRP-6 increases food intake in rats when administered intracerebroventricularly at 0.3, 1, and 3 nmol.

allo-DL-Threonine is a racemic mixture of the D and L isomers of the polar essential amino acid threonine.

Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.

Amino-PEG1-acid is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates.

m-PEG4-hydrazide is a PEG Linker.

m-PEG6-NHS ester is a PEG derivative containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

L-Methionylglycine is a dipeptide.

Ferbam is a pesticide.

Azido-PEG5-CH2CO2-t-Bu is a PEG derivative containing an azide group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

CS1 is a potent inhibitor of microtubule polymerization via interaction with the colchicine-binding pocket of tubulin, inducing unique histone phosphorylation patterns distinct from those induced by colchicine. CS1 is an antimitotic.

Cefadroxil anhydrous, L- is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic.

Leelamine, also known as NSC-2955, is a selective and potent inducer of hepatic cytochrome P450 2B activity. It is also an inhibitor of intracellular cholesterol transport.

Bromo-PEG2-phosphonic acid is a PEG Linker.

Bromo-PEG3-azide is a PEG derivative containing a bromide group and a terminal azide. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Bromo-PEG5-phosphonic acid diethyl ester is a PEG Linker.

Thiol-PEG3-t-butyl ester is a PEG derivative containing a thiol group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.