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Cat. No. Product Name Field of Application Chemical Structure
DC9409 SCH 546738
SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist with Ki of 0.4 nM .
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DC23426 SCH 412348
SCH 412348 is a potent and highly selective A2A receptor competitive antagonist with Ki of 0.6 nM.
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DC12427 SC-68448
SC-68448 (SC68448) is a potent, selective peptidomimetic antagonist of the integrin αvβ3 with IC50 of 1 nM, 100-fold selectivity over αIIbβ3.
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DC10961 S-C025
S-C025 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor) with IC50 of 0.12 nM.
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DC10962 S-230
S-C025 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor) with IC50 of 0.12 nM, inhibits 5-oxo-ETE-induced calcium mobilization in human neutrophils..
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DC9546 SBE-β-CD
SBE-β-CD (Sulfobutylether-β-Cyclodextrin; Captisol) is a chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs; Captisol is the trademark of SBE-β-CD registered by Ligand Pharmaceuticals.
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DC12467 SB772077B
SB772077B (SB-772077B, SB77, SB-772077-B) is a potent, selective Rho kinase (ROCK) inhibitor with IC50 of 5.6 nM and 6.0 nM for ROCK1 and ROCK2, respectively.
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DC21619 SB-699393
SB-699393 is a potent, selective and CNS penetrant B-Raf inhibitor with Kd of 7.2 nM.
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DC21614 SB-435495
SB-435495 is a potent, orally active inhibitor of Lp-PLA2 with IC50 of 0.06 nM.
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DC21613 SB-399885 hydrochloride
SB-399885 is a potent, selective, brain penetrant 5-HT6 receptor antagonist with pKi of 9.11 and 9.02 for human recombinant and native 5-HT6 receptors.
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DC8417 SB273005
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
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DC9316 SB 271046 (Hydrochloride)
SB271046 Hcl is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9.
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DC22410 SB269652
SB269652 is a potent, selective, negative allosteric modulator of dopamine D2 and D3 receptors, abolishes specific binding of [3H]nemanopride and [3H]spiperone to CHO-transfected D3 receptors with IC50 of1.86 and 0.18 nM.
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DC21611 SB-258585
SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes.
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DC9924 SB218078 Featured
SB218078 is an inhibitor of checkpoint kinase 1 (Chk1) that displays selectivity over other protein kinases (IC50 values are 15, 250 and 1000 nM for Chk1, cdc2 and PKC respectively).
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DC21620 SB 737050A
SB 737050A is a potent, selective 5-HT6 receptor antagonist to prevent relapse intio addiction..
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DC8878 SB 242084
SB 242084 is a potent and selective antagonist of 5-HT2C receptor.
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DC21608 SB 206553
SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes.
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DC12330 SB 204990
SB 204990 is a potent and specific inhibitor of ATP citrate lyase (ACLY) enzyme.
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DC24018 Satraplatin
Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis.
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DC21605 SAS-0132
SAS-0132 (SAS132) is a novel potent, subtype-selective, brain penetrant sigma 2 receptor/PGRMC1 ligand with Ki of 90 nM, 9-fold selectivity over sigma 1 receptors.
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DCAPI1384 Sarafloxacin HCl
Sarafloxacin HCl
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DC8104 SAR407899 HCl
SAR407899 Hcl is a potent, ATP-competitive ROCK inhibitor woth Ki value of 36 nM/41 nM for human ROCK/Rat ROCK respectively.
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DC12589 SAR260301
SAR260301 (SAR-260301, SAR 260301) is a potent, selective, ATP-competitive PI3Kβ inhibitor with IC50 of 52 nM in TR-FRET assays, with littile to no actiivty against PI3Kα/γ/δ (IC50=1,869/>10,000/403 nM, respectively).
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DC22414 SAR-216471 hydrochloride
SAR-216471 is a potent, highly selective, intravenous and oral, reversible P2Y12 receptor antagonist with binding IC50 of 17 nM.
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DC8628 Saquinavir Mesylate Featured
Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy.
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DC8627 Saquinavir Featured
Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy.
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DC20182 Sapropterin Dihydrochloride;Tetrahydrobiopterin Dihydrochloride, R-THBP Dihydrochloride
Sapropterin Dihydrochloride, a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4), is a phenylalanine hydroxylase activator.
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DC10444 Sapacitabine (CYC682) Featured
Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity.
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DC22222 SAN9812
SAN9812 (Carnostatine) is a potent, highly selective, competitive inhibitor of Carnosinase 1 (CN1) activity with Ki of 11 nM.
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