CB-1158 (INCB-01158) is a potent, selective, oral available Arginase inhibitor with IC50 of 98 nM.

Cazpaullone (9-Cyano-1-azapaullone) is a derivative of 1-Azakenpaullone, a potent, selective GSK3β inhibitor with IC50 of 8 nM, weakly inhibits CDK1/cyclin B and CDK5/p25 (IC50=0.5 and 0.3 uM).

CAY10595 is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki of 10 nM.

Cathepsin B inhibitor RC1 is a small-molecule that blocks the process of anthrax lethal toxin (LT) cytotoxicity, inhibits enzymatic activity of host cathepsin B that mediates the escape of toxins into the cytoplasm from late endosomes.

Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 µM.

CAT639 is an improved analog of ATV399 that exhibits improved β-cell viability and insulin secretion in the rat insulin-producing INS1E cells and primary rat dispersed islet cells, inhibits dimerization of iNOS.

Casopitant (GW679769) is a potent, centrally-acting neurokinin 1 (NK1) receptor antagonist (pKi=9.48) with antidepressant and antiemetic activities.

Carvedilol(BM14190) is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.

Carteolol is an antagonist of β-adrenergic receptors (Kd = 13 nM).

CARM1 inhibitor 9 is a potent, selective inhibitor of arginine methyltransferase 1 (CARM1, PRMT4) with IC50 of 94 nM.

Carisoprodol is a centrally acting skeletal muscle relaxant of the carbamate class and produces all the effects associated with barbiturate receptor ligands.

Cariporide is a selective Na+/H+ exchanger isoform 1 (NHE1) inhibitor (IC50 values are 0.05, 3 and 1000 μM for NHE1, NHE3 and NHE2 respectively).

Cardionogen 2 (CDNG2) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling.

Cardionogen 1 (CDNG1) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling.

Cardiogenol C is a small cell-permeable molecule that selectively and efficiently induce mouse embryonic stem cells (ESCs) to differentiate into cardiomyocytes with EC50 of 0.1 uM.

Carbosulfan inhibited relatively potently CYP3A4 and moderately CYP1A1/2 and CYP2C19 in pooled HLM (human livers). Carbosulfan activation is predominantly catalyzed in humans by CYP3A4.

Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties.

Carbetapentane citrate is a selective inhibitor of the cough, with mild atropine-like effect and local anesthesia effect.

Carbazochrome sodium sulfonate

Capzimin (Rpn11 inhibitor 3027) is a derivative of 8TQ, and potent and specific inhibitor of proteasome isopeptidase Rpn11 with IC50 of 0.34 uM, >7-fold improved potency over 8TQ (quinoline-8-thiol).

Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE).

Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM.

Caprooyl tetrapeptide-3 is a derivative of tetrapeptide-3 that is linked to caproic acid.

Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.

Canagliflozin 0.5 H2O(JNJ 28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.

Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.

CAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5.

CAM4712 (CAM-4712) is a potent and selective CK2α inhibitor with IC50 of 7 uM, exhibits cell growth inhibition in HCT116 cell line with IC50 of 10 uM.

CAM4066 (CAM-4066) is a potent and selective CK2α inhibitor with Kd of 0.32 uM and IC50 of 0.37 uM, shows significantly improved selectivity compared to other CK2α inhibitors. .

Calindol hydrochloride is a calcimimetic acting agent and positive allosteric modulator (agonist) of CaSR with EC50 of 0.31 uM (stimulated 3H IP accumulation in CHO cells at 2 mM Ca2+).