Inhibitor of Eukaryotic Translation; Antitumor Natural Product

Moderate alpha-l-fucosidase inhibitor

Natural microbial metabolite of isoflavone genistein, increasing the lifespan and improving the thermal and oxidative stress tolerance of C. elegans

Less active enantiomer of Elexacaftor

BAY-805 is a potent and selective USP21 inhibitor. BAY-805 is a non-covalent inhibitor with low nanomolar affinity for USP21 and high selectivity over other DUB targets as well as kinases, proteases, and other common off-targets.

Metabolite of VX-740

Vesicular monoamine transporter-2 (VMAT2) inhibitor, with 15-​fold greater affinity than GZ-​793A

Inactive control for VinSpinIn

Negative control for EED inhibitor EED226

FIT-039 is a potent, selective CDK9 inhibitor with IC50 of 5.8 uM for CKD9/cyclin T1, suppresses the replication of HSV-1 (IC50=0.69 uM).

Negative control compound for UNC3866 which is a potent antagonist of the methyllysine (Kme) reading function of the Polycomb CBX and CDY families of chromodomains

Negative control for UCSF924

Cell impermeant homolog of UCD38B, inhibitor of uPA (urokinase plasminogen activator)

Negative control for TP-004

Negative control for TP-238

Negative control for TP-040

Negative control for THPP-1

Novel potent and selective NUDT15 inhibitor (MG IC50 = 35 nM), potentiating the anti-HCMV efficacy of ganciclovir

Negative control for TH1760

Metabolite of Telmisartan

Novel novel anti-tuberculosis (TB) agent, possessing improved safety properties compared to bedaquiline

Cell permeable Cx43 hemichannel blocker, being used a control peptide for TAT-Gap19

Negative control for T3-CLK

Prodrug of ADAM17 inhibitor SN-4

Negative control for SGC-STK17B-1, showing IC50 > 10,000 nM against STK17B

Negative control for SGC-CLK-1

Negative control for SGC-CK2-1

Negative control for SGC-CAMKK2-1

Negative control for SGC-SMARCA-BRDVIII

Novel cell permeable CD45 phosphatase inhibitor; Prodrug of RWJ-60475