Natural inhibitor of the Na+/K+-ATPase sodium-potassium ion pump

Novel potent inhibitor of the natural function of FDX1, promoting a unique form of copper-dependent cell death

Novel AMPK activator, inhibiting mTOR signaling and autophagy stimulation, activating mutations in RAS or BRAF

Novel Inhibitor of Migration and Invasion of Osteosarcoma Cells Mediated by p53, Regulating EMT-Related Genes

Novel Inhibitor of Migration and Invasion of Osteosarcoma Cells Mediated by p53, Regulating EMT-Related Genes

Soluble secreted member of the tumor necrosis factor receptor superfamily, inhibiting osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, leading to excess accumulation of bone and cartilage

Novel inhibitor of osteoclast differentiation through regulating MAPKs and Akt signaling pathways

Inhibitor of the glycan-processing enzyme endoplasmic-reticular glucosidase

Novel cGMP phosphodiesterase (cGMP-PDE) inhibitor

Novel potent, orally efficacious, dual inhibitor of cMET and RON kinases

Inhibitor of the influenza neuramidase enzyme, blocking neuraminidases on the surfaces of influenza viruses, interfering with host cell release of complete viral particles

Second-generation taxane derivative with potential antineoplastic activity, binding to and stabilizing tubulin molecules, inhibiting cell division and cellular proliferation

Peripheral weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist, preventing from being absorbed and entering the central nervous system

Inhibitor of an enzyme responsible for the multidrug resistance phenotype in the yeast Saccharomyces cerevisiae.

Novel potent dual orexin 1/2 receptor (OX1/2R) antagonist for the treatment of insomnia

Novel sodium/calcium exchanger (NCX) inhibitor

Lipoglycopeptide Antibacterial, acting as a inhibitor of Cytochrome P450 2C19/2C9, and a inducer of Cytochrome P450 3A4/2D6

Selective p38alpha and p38beta kinase inhibitor

CB1 allosteric modulator

Negative allosteric modulator at the CB1 receptor

Novel mixed κ/μ receptor antagonist. having therapeutic potential for the treatment of depression and other stress-induced conditions

Collagen immunostain

Novel Potent, Well Tolerated, and Orally Active Protective Agent against Aminoglycoside-Induced Hearing Loss

Novel negative allosteric modulator (NAM) of mGlu4, being isomerized with blue-light/dark cycles with fast relaxation

Inhibitor of calmodulin action in calcium regulation

Antioxidant and free radical scavenger, attenuating edema formation, and subsequent tissue damage following cortical contusion

Metabolite of Cilostazol

Novel potent inhibitor of protein-protein interactions

Potent, selective, and orally active prostaglandin D2 receptor antagonist

Novel selective EP3 receptor agonist