Natural antiproliferative, antifungal, antitumor agent, suppressing the epithelial-mesenchymal transition (EMT) process and inhibiting activation of the FAK/Src/STAT3 signaling pathway in A375 cells, targeting RACK1 to suppress cancer cell migration

Novel selective inhibitor of Hap2/3/4/5p mediated transcription in vivo.

Novel inhibitor of cathepsin K (CatK)

Novel Wnt inhibitor, blocking Wnt signaling downstream of beta-Catenin

Novel HaloPROTAC degrader, inducing degradation of HaloTag fusion proteins

Selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) modulator with antilipidemic activity

Antimalarial, binding to plasmpesin, a haemoglobin degrading enzyme unique to the malarial parasites

Topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities, inducing phospholipase A2 inhibitory proteins, activating gene expression of anti-inflammatory proteins mediated via the corticosteroid receptor response element

Herbicide, being used for the control of broad-leaved weeds in cereals and oilseed rape

Novel hemagglutinin (HA) protein inhibitor, inhibiting entry and replication of diverse influenza viruses via the HA protein, showing potent antiviral activity against diverse H1N1, H5N1, and H3N2 influenza viruses encoding HA proteins from both groups 1

Inhibitor of monoamine oxidase (MAO)

Novel inhibitor of STAT3 activation, inhibiting head and neck cancer cell proliferation in a dose dependent manner

Inhibitor of acetic acid-induced writhing response

Novel water-soluble and biocompatible small-molecule near-infrared II (NIR-II) fluorescent dye

Novel class of selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor

Novel class of selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor

Novel full H1 agonist

Novel Rho-associated coiled coil-formed protein kinase (ROCK) inhibitor, exerting strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys

Novel Rho-associated coiled coil-formed protein kinase (ROCK) inhibitor, exerting strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys

Novel bacterial DNA gyrase inhibitor, exhibiting antimicrobial activity and inhibiting bacterial cell division

AMPA antagonist

GX-936 analog, antagonist of voltage-gated sodium 1.7 (Nav1.7) channels

Novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2

Novel inhibitor of Nav1.7

Novel modulator of NF-Y transcription, inhibiting the binding of NF-Y to DNA, blocking cellular proliferation and cell cycle progression, interacting with a variety of CCAAT-containing promoters leading to p53-independent cell cycle arrest

Novel NAD+-competitive Sirt2 inhibitor

Novel polo-like kinase (PLK1) inhibitor

Novel potent and selective inhibitor of the cytochrome bc1 complex of mitochondrial electron transport in P. falciparum

Novel inhibitor of mitosis and cytokinesis in T. brucei which causes human African trypanosomiasis (HAT)

Novel Inhibitor of GSK3beta