Activator of β2 and β3 subunit containing channels of the GABAA receptor complex, stimulating the production of GABA(A) active neurosteroids

TRPA1 channel agonist

Novel selective FTO inhibitor

Natural potent antiviral agent, significantly inhibiting coxsackievirus group B (CVB) replication both in vivo and in vitro

Novel anticancer agent

Cell-impermeant viability indicator, as high-affinity nucleic acid stain that is weakly fluorescent until bound to DNA and emits red fluorescence (excitation/emission maxima ~528/617).

Novel inhibitor of PORCN, inhibiting ß-catenin reporter activity in a dose-dependent manner

H-89 analog as PKA and AKT1 inhibitor with specificity on no longer inhibiting CAMK2B and neither affecting viability of mice nor causing any detectable tissuedamage at the dose given

Selective estrogen receptor modulator (SERM), exhibiting estrogen agonism in certain tissues and estrogen antagonism in others

Novel Highly Soluble σ1 Receptor Antagonist for Pain Management

Serotonin 5-HT2A Agonist

Broad-spectrum, topical macrolide antibiotic, diffusing through the bacterial cell membrane and reversibly binding to the 50S subunit of the bacterial ribosome

Precursor of adrenaline, suppressing the locomotor stimulation by MAO inhibitor

Anti-HBV agent, showing activities on HepG 2.2.15 cell line in vitro

Novel potent inhibitor of recombinant human and mouse Transglutaminase enzyme activity, mainly TG2 and the close related enzyme TG1

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Novel thermosensitive fluorescent dye, visualizing thermogenesis in stimulated single-cell brown adipocytes

Carbapenem antibiotic, inhibiting cross-linking of the peptidoglycan layer of bacterial cell walls by blocking penicillin-binding proteins (PBPs)

The first ERβ-targeted near-infrared (NIR) inherently fluorescent probe, showing the advantages of high ERβ selectivity, good optical properties, and excellent ERβ imaging capability in living cells

Novel Activator of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer

Novel PROTAC Estrogen-related Receptor α (ERRα) Degrader

Novel degrader of ERK1/2, eliciting downregulation of phospho-ERK1/2 signal.

Negative control for ERK Inhibitor II AOB6420

Analogue of the lipid A portion of the endotoxin lipopolysaccharide (LPS) with potential immunomodulating activity, binding to the Toll-like receptor (TLR)/CD14/MD2 receptor complex, inhibiting the activation of the receptor complex by LPS

Novel ATP-competitive Selective c-Jun N-terminal kinase (JNK) inhibitor

Natural Nsp15 inhibitor against SARS-COV2

Novel potent inhibitor of ERCC1-XPF activity, targeting DNA repair in tumor cells

Novel ErbB type I receptor tyrosine kinase inhibitor for the treatment of hyperproliferative diseases

Novel competitive inhibitor of ERAP1 aminopeptidase activity

Novel Selective ERAP1 Inhibitor