Retinoic acid receptor (RAR) subtype α-selective agonist

Selective squalene synthase (SQS) inhibitor

Novel Oral Selective Estrogen Receptor Degrader with Highly Improved Antitumor Effect and Favorable Druggability

Novel SMYD2 inhibitor

Novel selective SMYD2 inhibitor

Inactive isomer of EPZ005687 and can be used as the negative control for EPZ005687

Potent, selective, high efficacy 5-HT1A receptor agonist

Novel inhibitor of extracellular polymeric substances (EPS)

Mucolytic and bronchospasm relieving agent

The precursor of the nocardicins

Second-generation antihistamine and mast cell stabilizer, being highly selective for the H1 receptor

Novel stabilizer of 14-3-3 PPIs, Diastereoepimer of aminopeptidase inhibitor bestatin

Novel selrctive SETD8 inhibitor without inhibiting G9a, SETD7, RmtA, and PRMT1

The first potent and specific inhibitor of a single Eph isoform EphB3

Novel clickable potent and specific inhibitor of EphB3

Potent and selective covalent inhibitor of receptor tyrosine kinase EphB1

Novel agonist of EphA2 receptor tyrosine kinase

Novel potent and selective leucyl-tRNA synthetase inhibitor

Vitamin E derivative, suppressing inflammation during hepatic ischemia-reperfusion injury and exerting hepatoprotective effects

Novel, potent, and selective Factor XIa inhibitor

Unnatural verticilide enantiomer, inhibiting type 2 ryanodine receptor-mediated calcium leak and being antiarrhythmic.

Novel inhibitor of Ectonucleoside Triphosphate Diphosphohydrolase 5 (ENTPD5)

Novel inhibitor of Ectonucleoside Triphosphate Diphosphohydrolase 5 (ENTPD5)

Dopamine D2-receptor agonist for the treatment of extrapyramidal disorders, also being an antiparkinson agent

PGE2 analog, inhibiting gastric acid secretion

Novel potent inhibitor of ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1 or NPP1), showing good in vitro potency, stability in SGF/SIF/PBS, selectivity, ADME properties and pharmacokinetic profile and finally potent anti-tumor response in viv

Novel oral inhibitor of angiogenic and proliferation kinases, having activity in recurrent, platinum resistant ovarian cancer

Novel potent inhibitor of eleven-nineteen leukemia (ENL) protein, selectively targeting the ENL YEATS domain

Sodium/hydrogen exchange inhibitor

Novel modulator of the PIN1 accumulation, selectively modifying PIN1 basal plasma membrane targeting in Arabidopsis with minimal effects on apical plasma membrane proteins