Selective kynurenine aminotransferase 2 (KAT2) inhibitor

PET precursor for NNC112

Less active enantimer of Bambuterol

Potent and selective inhibitor of PI 3-kinase ß (PI3-Kß)

Potent beta-adrenoreceptor antagonist

Natural flavonoid from the stem bark of Bolusanthus speciosus

The First Selective Orthosteric GluK3 Antagonist

Novel potent orally available allosteric TSH receptor (TSHR) agonist

Novel σ Receptor Agonist with Neuroprotective Effect

Elongation factor P (EF-P) fuction modifier

More active enantiomer of praziquantel as potent anthelmintic

Enhancer of memory function

Selective Dopamine D3 Receptor Antagonist

More active R diastereomer of Pam2Cys, acting as a potent TLR2 agonist

Inhibitor of dopamine beta-hydroxylase

Competitive Specific Inhibitor of sphingosine kinase 2 (SK2)

R-Enantiomer of folcisteine, a plant growth regulator

Negative control for UNC6852

IMP-1710 (IMP1710) is a potent, selective, covalent UCHL1 inhibitor with IC50 of 38 nM.IMP-1710 demonstrated exquisite selectivity in a cross-screening against 20 DUBs.IMP-1710 can profile activity of endogenous UCHL1 with excellent selectivity in cell types including endothelial cells (EA.hy926) and adenocarcinoma human alveolar basal epithelial cells (A549).IMP-1710 demonstrated >50% fibroblast–myofibroblast transition (FMT) inhibition (IC50=740 nM) in idiopathic pulmonary fibrosis (IPF), as well as αSMA inhibition.IMP-1710 is a powerful and selective probe to explore UCHL1 activity with potential application to substrate identification, mode of action studies, and cellular target profiling.

KB-R7943 mesylate is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 mM).

An aminoglycoside antibiotic similar in structure to gentamicin B1.

Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).

Tematropium(CDDD3602) is a soft anticholinergics.

1-Methoxy PMS is an electron mediator for NAD(P)H-tetrazolium salt.

N-Type calcium channel inhibitor

Novel potent and selective oxytocin receptor antagonist

Micafungin(FK463) is an echinocandin antifungal drug, Micafungin inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls.

Avibactam sodium(NXL-104) is a non-β-lactam β-lactamase inhibitor antibiotic.

UoS12258 (UoS-12258) is a selective, positive allosteric modulator of the AMPA receptor with pEC50 of 5.6.

LOXO-101 is a small molecule that was designed to block the ATP binding site of the TRK family of receptors, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.