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Cat. No. Product Name Field of Application Chemical Structure
DC71023 CP-424174
CP-424174 is a reversible inhibitor against IL-1β processing with an IC50 of 210 nM.CP-424174 indirectly inhibits NLRP3.
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DC71022 CP 93129 dihydrochloride
CP 93129 dihydrochloride is a potent 5HT1B receptor agonist. CP 93129 dihydrochloride has the potential for parkinson's disease research.
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DC71021 Coumarin-SAHA
Coumarin-SAHA is a fluorescent probe for determining the binding affinities (kd) and the dissociation off-rates (koff) of the HDAC8-inhibitor complexes.
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DC71020 Coumarin hydrazine
Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468 nm) to label cellular protein- and lipid-bound carbonyls.
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DC71019 Cladosporin
Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin completely inhibits growth of severa dermatophytes on agar medium at a concentration of 75 μg/mL.
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DC71018 CL 218872
CL 218872 is a selective and orally active benzodiazepine of α1 subunit-containing GABAAreceptor with a Ki of 130 nM. CL 218872 exerts anxiolytic and anticonvulsant in vivo.
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DC71017 CCW16
CCW16 is the covalent ligand for the E3 ubiquitin ligase RNF4. CCW16 can be used in the synthesis of protein degraders.
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DC71016 CC214-2
CC214-2 is a potent and dual inhibitor of mTORC1/mTORC2. Mycobacterium tuberculosis modulates mammalian target of rapamycin (mTOR) signaling to impede autophagy. CC214-2 has the potential to shorten the duration of TB.
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DC71015 Cardanol monoene
Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can induce mitochondria-associated apoptosis in human melanoma cells.
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DC71014 C6 L-threo Ceramide
C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. C6 L-threo Ceramide significantly inhibits IL-4 production in T cells. Anti-allergic agents.
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DC71013 BOC-L-Phenylalanine-13C
BOC-L-Phenylalanine-13C is a 13C-labeled BOC-L-Phenylalanine. BOC-L-Phenylalanine is a derivative of Phenylalanine.
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DC71012 BNS
BNS is a cell penetrant, potent and selective PHD2 (prolyl-hydroxylase 2) inhibitor.
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DC71011 Bisindolylmaleimide II
Bisindolylmaleimide II is a general inhibitor of all PKC subtypes.
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DC71010 Bilirubin Conjugate disodium
Bilirubin Conjugate disodium is a ditaurate derivative of Bilirubin. Bilirubin, a major end product of heme breakdown, is an important constituent of bile.
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DC71009 BAY-R 1005
BAY-R 1005, an immunoenhancing agent, is a synthetic glycolipid analogue (GLA), which is supposed to modulate antibody synthesis.
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DC71007 Aucuparin
Aucuparin, a natural product found in Sorbus aucuparia, inhibits pulmonary fibrosis in a bleomycin (BLM)-induced lung fibrosis mouse model. Anti-inflammatory activity.
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DC71006 ATL-801
ATL-801, an A2B receptor selective antagonist, ameliorates murine colitis.
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DC71005 AS-136A
AS-136A is an orally active non-nucleoside inhibitor of the measles virus RNA-dependent RNA polymerase (RdRp) with an IC50 of 2 µM for measles virus.
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DC71003 AP5 sodium
AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research.
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DC71001 Alendronate sodium
Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis.
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DC71000 Alatrofloxacin
Alatrofloxacin, the parenteral prodrug of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity.
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DC70999 A-784168
A-784168 is a potent and orally active inhibitor of vanilloid receptor type 1 (TRPV1). Vanilloid receptor type 1 (TRPV1) is a ligand-gated nonselective cation channel that is considered to be an important integrator of various pain stimuli such as endogenous lipids, capsaicin, heat, and low pH. A-784168 has good CNS penetration.
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DC70998 6-trans-Leukotriene B4
6-trans-leukotriene B4 is a neutrophil chemotaxin in the guinea pig dermis.
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DC70997 4-Hydroxyhippuric acid
4-Hydroxyhippuric acid is a by-product of metabolism of polyphenols and increases the microflora activity related to the refeeding.
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DC70995 2-Hexyl-4-pentynoic acid
2-Hexyl-4-pentynoic acid ((±)-2-Hexyl-4-pentynoic acid), valproic acid (VPA) derivative, exhibits potential roles of HDAC inhibition (IC50=13 µM) and HSP70 induction. Potent neuroprotective effects. 2-Hexyl-4-pentynoic acid causes histone hyperacetylation and protect against glutamate-induced excitotoxicity in cultured neurons.
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DC70994 2-Fluoropalmitic acid
2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines.
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DC70993 2′,3′,5′-Triacetyl-5-azacytidine
2′,3′,5′-Triacetyl-5-azacytidine is an orally active prodrug of 5-Azacytidine. 5-Azacytidine is an inhibitor of DNA methyltransferase.
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DC70991 17-PA
17-PA is a selective antagonist of neurosteroid potentiation and direct gating of GABAA receptors.
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DC70990 16-Epiestriol
16-Epiestriol is a metabolite of the endogenous estrogen estrone with antibacterial and anti-inflammatory effects.
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DC70988 14(S)-HDHA
14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway.
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