Dihydropleuromutilin is a reduced product of Pleuromutilin, which is active against gram-positive bacteria and shows lower toxicity.

Dihydrodaunomycin has antibacterial and antitumor activities.

Deshydroxyethoxy ticagrelor (AR-C124910) is a metabolite of Ticagrelor. Timegadine hydrochloride is an orally active inhibitor for COX and lipo-oxygenase, that inhibits COX in washed rabbit platelets and rat brain with IC50 of 5 nM and 20 μM, inhibits lipo-oxygenase in in horse and washed rabbit platelets with IC50 of 100 μM. Timegadine hydrochloride exhibits anti-arthritis activity.

Deprodone is an active compound. Deprodone inhibits key processes such as bacterial cell wall synthesis by interacting with the hydrolase and transferase proteins of methicillin-resistant Staphylococcus aureus (MRSA). Deprodone is used in research on anti-MRSA infection, inflammatory skin disorders, bowel disease, and fatty acid metabolism disorders.

DC-159a is an 8-methoxyfluoroquinolone with broad-spectrum antimicrobial activity, especially against Gram-positive pathogens. DC-159a against Peptostreptococcus, Clostridium difficile, and Bacteroides fragilis with MIC90 values of 0.5, 4, and 2 μg/mL, respectively.

Dactylocycline E has anti-Gram-positive bacteria activity.

Colupulone is a β-acid resin component found in hops (Humulus lupulus) and exhibits antibacterial and anti-larval activity against Culex mosquitoes. Colupulone can be used in studies related to infectious diseases.

Cholic acid anilide, a Narylcholan-24-amide, is a potent inhibitor of C. difficile spore germination with an IC50 value of 1.8 μM in the spore germination assay conducted in Sodium phosphate media containing 6 mM Taurocholate and 12 mM Glycine. Cholic acid anilide has the potential for C. difficile infections research.

Chloramphenicol 3-acetate is the main intermediate in the biodegradation of CAP, formed by the acetylation of the 3-hydroxy group of CAP through chloramphenicol acetyltransferase, this is a common resistance mechanism that microbes have against chloramphenicol.

Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin.

Cefclidin (Cefclidine) belongs to the cephalomycin-type compound.

Cefbuperazone belongs to the cephalomycin-type compound.

C12-rrw-NH2 (Compound Lip7) is an antibacterial agent against gram-positive bacteria, especially against Methicillin. Sildenafil is a potent phosphodiesterase type 5 (PDE

BPH-608 is a bacterial undecenyl diphosphate synthase (UPPS) inhibitor (IC50=590 nM) with antibacterial activity.

BAS-118 is a benzamide derivative with antibacterial activity. The MIC50, MIC90 and MIC ranges of BAS-118 for 100 randomly selected isolates of Helicobacter pylori are ≤0.003, 0.013 and ≤0.003-0.025 mg/L, respectively. BAS-118 is promising for research of anti-H. pylori agent.

BAR-072 is a small-molecule inhibitor targeting TraE, with a KD of 2.7 µM. It significantly inhibits the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 shows promise as a candidate compound for blocking the spread of bacterial resistance genes and holds potential for research in infectious disease and antimicrobial resistance control.

Bactobolin B (Alanylbactobolin) is a chlorine-containing antibiotic with antitumor activities.

Bacimethrin (NSC 66577) is an antibacterial agent and is thiamin biosynthesis antagonist.Bacimethrin inhibits bacterial and yeast growth.

Armentomycin (L-Armentomycin) is a nonprotein amino acid with antibiotic properties. Armentomycin mainly acts against Gram-negative bacteria.

Arizonin B1, a microbial metabolite, is an antibiotic with anti-Gram-positive bacterial activities.

Apoptosis inducer 33 (Compound H2) is a hydrazone derivative. Apoptosis inducer 33 has antioxidant and antibacterial activity that inhibits the growth of Staphylococcus aureus, Escherichia coli and Candida albicans. Apoptosis inducer 33 inhibits tumor cells proliferation and induces apoptosis, which can be used in the study of cancer.

apo-Enterobactin is a derivative of Enterobactin.

Antibacterial synergist 3 is a dual-acting inhibitor of biofilm (IC50 of PAO1: 0.40 μM and IC50 of PA14: 1.45 μM). Antibacterial synergist 3 reduces virulence production by inhibiting the quorum sensing (QS) system and induces iron deficiency in P. aeruginosa PAO1. Antibacterial synergist 3 enhances the efficacy of Tobramycin and Ciprofloxacin in a mouse wound infection model. Antibacterial synergist 3 can be used for the research of P. aeruginosa infections.

Angolamycin is a basic macrolide antibiotic active against Gram-positive bacteria.

Amidinomycin is mainly resistant to Gram-positive bacteria (weak).

Albonoursin, a microbial secondary metabolite, is an antibacterial peptide. Albonoursin displays antibacterial and antitumor activities.

Alahopcin is a dipeptide antibiotic with a broad antibacterial spectrum.

AK-968-11563024 is an inhibitor of marine V. vulnificus NAT [ (VIBVN)NAT] with an IC50 of 18.86 µM. NATs (Arylamine N-acetyltransferases) in marine V. vulnificus plays a role in drug metabolism, contributing to the development of drug resistance. Therefore, AK-968-11563024 can be utilized in research related to drug resistance.

9-tert-Butyldoxycycline exhibits immunomodulatory activity, alters the polarization states polymorphonuclear neutrophils, and ameliorates the inflammatory response in ischemia-reperfusion injury model. 9-tert-Butyldoxycycline is the ligand for ‘Tet-On’ switch system.

8-Nonynoic acid (non-8-ynoic acid) is a fatty acid that belongs to the group of octynoic acids. It exhibits antibacterial activity against gram-positive bacteria by binding to bacterial fatty acids. 8-Nonynoicacid also inhibits growth of gram-negative bacteria by inhibiting the synthesis of fatty acids. It is also capable of inhibiting growth of both aerobic and anaerobic bacteria in biochemical assays.