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Cat. No. Product Name Field of Application Chemical Structure
DC77956 Obudanersen
Obudanersen is an antisense oligonucleotide targeted to ubiquitin protein ligase E3A-antisense transcript (UBE3A-ATS). It is used for the study of Angelman syndrome.
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DC77955 Obudanersen sodium
Obudanersen sodium is an antisense oligonucleotide targeted to ubiquitin protein ligase E3A-antisense transcript (UBE3A-ATS). It is used for the study of Angelman syndrome.
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DC77954 Obeversen sodium
Obeversen sodium is an antisense oligonucleotide that inhibits the synthesis of Diacylglycerol acyltransferase 2 (DGAT-2). Obeversen sodium can be used in the research of nonalcoholic fatty liver disease.
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DC77953 S 3578 sulfate
S 3578 (sulfate) is a broad-spectrum antibacterial agent, particularly effective against methicillin-resistant Staphylococcus aureus (MRSA) (MIC = 0.78-3.13 μg/mL) and Pseudomonas aeruginosa (MIC = 1.56-6.25 μg/mL). S 3578 (sulfate) can be used in the research of infectious conditions.
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DC77952 SPAA-52 ammonium
SPAA-52 (ammonium) is a low molecular weight protein tyrosine phosphatase (LMW-PTP) inhibitor (IC50 = 4 nM; IC50 = 1.2 nM). SPAA-52 (ammonium) can be used in the research of diabetes mellitus.
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DC77951 FAPI-P8PN
FAPI-P8PN is a fibroblast activation protein (FAP) inhibitor (IC50=3.6 nM). FAPI-P8PN is promising for research of FAP-overexpressing solid tumors.
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DC77950 OZO-H
OZO-H is a GST inhibitor. OZO-H is an OZO derivative with potent anti-cancer effects. OZO-H releases JNK1 from GST-JNK1 complex. OZO-H induces JNK1 phosphorylation and activates c-Jun in cancer cells.
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DC77949 OZO-Cl
OZO-Cl is an OZO derivative. OZO-Cl has anti-cancer activity. OZO-Cl significantly decreases the intracellular glutathion S-transferase Pi (GST) activity. OZO-Cl exhibits cytotoxicity to cancer cell lines, with IC50s of 150 and 120 μmol/L in Panc-1 and K562 cells respectively.
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DC77948 BO 1341
BO 1341 is a PBPs inhibitor and an antipseudomonal semisynthetic cephalosporin. BO 1341 exhibits antibacterial activity against most Gram-negative bacteria, such as Pseudomonas aeruginosa (MIC90: 1.56 μg/mL), Pseudomonas maltophilia (MIC50: 1.56 μg/mL), and Acinetobacter calcoaceticus (MIC90: 3.13 μg/mL) . BO 1341 can be used in the research of infectious diseases.
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DC77947 DQ 2556
DQ 2556 is a semi-synthetic cephalosporin antibiotic. DQ-2556 exhibits significant activity against both Gram-positive and Gram-negative bacteria, particularly Gram-positive bacteria and Enterobacteriaceae infections. DQ 2556 exerts its bactericidal effect by interfering with cell division. DQ-2556 has a strong affinity for the penicillin-binding proteins (PBPs) of Escherichia coli: PBP1A/1B (IC₅₀ = 0.57-0.73 μg/mL) and PBP3 (IC₅₀ = 0.088 μg/mL). DQ-2556 demonstrates significant in vivo protective effects. DQ-2556 can be used in the development of injectable cephalosporins.
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DC77946 ME-1036
ME-1036 (CP-5609) is a carbapenem antibiotic. ME-1036 against resistant Gram-positive organisms, including Methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococci (VRE), and ESBL-producing E. coli and K. pneumoniae but is not effective against P. aeruginosa.
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DC77945 Nucresiran
Nucresiran is a siRNA that inhibits hepatic synthesis of both wild-type and variant TTR mRNA.
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DC77944 Nucresiran sodium
Nucresiran sodium is a siRNA that inhibits hepatic synthesis of both wild-type and variant TTR mRNA.
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DC77943 Nivudirsen
Nivudirsen is an antisense oligonucleotide that can promote the synthesis of functional dystrophin protein.
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DC77942 Nivudirsen sodium
Nivudirsen sodium is an antisense oligonucleotide that can promote the synthesis of functional dystrophin protein.
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DC77941 E3 Ligase Ligand-linker Conjugate 179
E3 Ligase Ligand-linker Conjugate 179 is an E3 ubiquitinase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 179 can be used to synthesize JV8.
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DC77940 Nelitolimod
Nelitolimod, a CpG oligonucleotide, is a TLR9 agonist.
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DC77939 Nelitolimod sodium
Nelitolimod sodium, a CpG oligonucleotide, is a TLR9 agonist.
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DC77938 (S,R,S)-AHPC-amide-PEG5-C2-azide
(S,R,S)-AHPC-amide-PEG5-C2-azide (VH032-CO-(CH2)2-(O-CH2-CH2)5-azide) is a PROTAC linker that can be used to design PROTACs.
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DC77937 FBnG-amino-PEG3-C2-azido
FBnG-amino-PEG3-C2-azido is a tag-linker conjugate that incorporates a degradation tag FBnG and a glycol linker (Amino-PEG3-C2-Azido). FBnG-amino-PEG3-C2-azido can be used for synthesis of GPX4-AUTAC
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DC77936 Duazomycin sodium
Duazomycin (Duazomycin A) sodium is a glutamine antagonist. Duazomycin sodium can significantly enhance the effectiveness of 6-Mercaptopurine (6-MP) in experimental allergic encephalomyelitis (EAE) without increasing toxicity.
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DC77935 Movronersen
Movronersen is an antisense oligonucleotide targeted to α-synuclein.
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DC77934 Movronersen sodium
Movronersen sodium is an antisense oligonucleotide targeted to α-synuclein.
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DC77933 Mivelsiran
Mivelsiran is a siRNA targeted to amyloid-beta precursor protein (APP). It is used for the study of Alzheimer's disease.
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DC77932 Mivelsiran sodium
Mivelsiran sodium is a siRNA targeted to amyloid-beta precursor protein (APP). It is used for the study of Alzheimer's disease.
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DC77931 Lufepirsen
Lufepirsen is an unmodified antisense oligonucleotide targeted to Connexin43 (Cx43). Connexin43 is a specific protein in the eye, which plays a role in wound healing.
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DC77930 Lufepirsen sodium
Lufepirsen sodium is an unmodified antisense oligonucleotide targeted to Connexin43 (Cx43). Connexin43 is a specific protein in the eye, which plays a role in wound healing.
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DC77929 Lixadesiran
Lixadesiran is a siRNA in STP705. It targets to COX-2. STP705 is composed of 2 siRNA oligonucleotides (Pixofisiran and Lixadesiran) that individually target TGF-β1 and COX-2 mRNA.
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DC77928 Lixadesiran sodium
Lixadesiran sodium is a siRNA in STP705. It targets to COX-2. STP705 is composed of 2 siRNA oligonucleotides (Pixofisiran and Lixadesiran) that individually target TGF-β1 and COX-2 mRNA.
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DC77927 Litenimod
Litenimod is potent type B agonist of toll Like receptor 9 (TLR9), triggering both innate and adaptive immune response.
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