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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC72584 | M47 Featured |
M47 is a small molecule that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer.
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| DC73063 | MU-UNMC-2 Featured |
MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells.
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| DC73397 | BPRCX807 |
BPRCX807 (BPRCX-807) is a highly selective and potent CXCR4 antagonist with binding IC50 of 40.4 nM and EC50 of 48.1 nM for cell-mobility activity in the chemotaxis assays, inhibits CXCL12-mediated cell signaling pathway.
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| DC73396 | BPRCX714 |
BPRCX714 (BPRCX 714) is a highly selective and potent CXCR4 antagonist with binding IC50 of 34.2 nM, effectively inhibits CXCL12-induced movement of CCRF-CEM cells with EC50 of 13.7 nM.
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| DC31451 | CCS-1477(CBP-IN-1) Featured |
CCS-1477 is a potent and selective p300/CBP bromodomain inhibitor, is targeted & differentiated from BET inhibitors in prostate cancer cell lines in vitro. Combination of CCS1477 & JQ1 resulted in a highly synergistic inhibitory effect on proliferation in normal 22Rv1 cells. Global gene expression analysis revealed significantly fewer altered genes after CCS1477 (27 up, 119 down) compared to JQ1 (196 up, 655 down).
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| DC7723 | OTS-964 Featured |
OTS964 is a novel TOPK(T–lymphokine-activated killer cell–originated protein kinase) inhibitor.
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| DC42537 | ALC-0315 Featured |
ALC-0315 is an ionisable aminolipid that used for mRNA compaction and aids mRNA cellular delivery. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles.
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| DC60898 | 3-Hydroxycholesta-5,24-dien-7-one; 3β-form, Ac Featured |
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| DC60897 | Cholest-7-en-3-ol,acetate, (3b)- (9CI) Featured |
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| DC60896 | 7,8-Didehydrocholesterol Acetate Featured |
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| DC60895 | 7-p-Toluenesulfonylhydrazide Cholesterol 3-Acetate Featured |
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| DC60894 | 7-Oxo Cholesterol 3-Acetate Featured |
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| DC60893 | 3-Keto Cholesterol Featured |
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| DC60892 | 7-Keto Cholesterol Featured |
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| DC60891 | 4-Methyl-cholesterol Featured |
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| DC43955 | 4α-Methylcholesterol Featured |
4α-Methylcholesterol is a Cholesterol derivative. 4α-Methylcholesterol can oxidize 3-hydroxy steroid, with the apparent Km of 12.6 μM.
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| DC60890 | 22a-Hydroxy Cholesterol Featured |
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| DC67628 | NMDC-Cholesterol Featured |
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| DC21557 | RB-011 Featured |
A small molecule that disrupt 14-3-3 dimers at low micromolar concentrations and induce rapid down-regulation of Raf-MAPK and PI3K-Akt signaling in Jurkat cells.
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| DC60889 | 3β-Acetoxy-5α-cholesta-7,24-diene Featured |
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| DC60887 | (3β,5α)-Cholesta-8(14),24-dien-3-ol Featured |
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| DC60888 | DESMOSTEROL ACETATE Featured |
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| DC60881 | 5alpha-cholestanyl-(3beta)-hydrogen sulfate Featured |
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| DC36443 | DC-Chol hydrochloride Featured |
DC-Chol hydrochloride is a cationic lipid. DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. DC-Chol hydrochloride induces the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. DC-Chol hydrochloride can enhance the body's immune response to antigens. DC-Chol hydrochloride is used as a gene delivery vector. DC-Chol hydrochloride can be used in research in areas such as hepatitis B vaccines to improve vaccine immunity.
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| DC60885 | 5alpha-Cholest-7-en-3beta-ol Featured |
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| DC60886 | 5-alpha-cholest-7,24-dien-3beta-ol Featured |
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| DC45677 | 5α-Cholesta-7,24-dien-3β-ol Featured |
5α-Cholesta-7,24-dien-3β-ol, a sterol, can be found in hamster cauda epididymal mature spermatozoa.
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| DC32956 | Desmosterol Featured |
Desmosterol is an endogenous agonist of RORgamma; Intermediate in the synthesis of cholesterol.
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| DC12188 | Lathosterol Featured |
Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis.
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| DC12199 | Cholestenone Featured |
Cholestenone is the intermediate oxidation product of cholesterol.
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