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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC46898 | Nerindocianine |
Nerindocianine is a fluorescent diagnostic contrast agent. Nerindocianine is highly hydrophilic and is primarily metabolized by the kidneys, allowing for a non-invasive intraoperative ureteral imaging.
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| DC46897 | Omzotirome |
Omzotirome (TRC150094), a functional analog of iodothyronines, can be used for the research of hyperlipidaemia (WO2008149379).
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| DC46896 | Biotin-NH-PSMA-617 |
Biotin-NH-PSMA-617 is a biotin-tagged PSMA-617. PSMA-617 is a small molecule targeting the prostate-specific membrane antigen (PSMA), which is directly expressed by the tumor cells .
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| DC46895 | (R)-eIF4A3-IN-2 |
(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM.
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| DC46894 | (S)-ATPO |
(S)-ATPO is the (S)-enantiomer of ATPO, which is a competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
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| DC46893 | Triton X-45(n=4) |
Triton X-45 (n=4), a nonionic surfactant with a low hydrophile-lypophile balance (HLB) value and dispersible in aqueous solution at room temperature, has a Krafft point above the room temperature. Triton X-45 has the potential for the research of the hepatitis C virus (HCV).
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| DC46892 | D-Erythritol 4-phosphate |
D-erythritol 4-phosphate is a phosphorylated component isolated from the hydrolysate.
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| DC46891 | [18F]AZD4694 Precursor |
[18F]AZD4694 Precursor is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques.
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| DC46890 | 2-Deoxy-D-glucose 6-phosphate |
2-Deoxy-D-glucose 6-phosphate is an intermediate of 2-deoxy-D-glucose (2-DG) . 2-Deoxy-D-glucose is incorporated into glycogen.
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| DC46889 | FP-Biotin |
FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads.
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| DC46888 | ACT-373898 |
ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist.
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| DC46886 | 4-Nitrophenyl Laurate |
4-Nitrophenyl Laurate is a class of 4-nitrophenyl ester, which can be used as enzyme substrate.
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| DC46885 | Mivorilaner |
Mivorilaner, an antineoplastic, can be used for the research of veterinary medicine (WO2012155676,Example 245).
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| DC46884 | UBE2T/FANCL-IN-1 |
UBE2T/FANCL-IN-1 is a potent inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation that sensitizes cells to the DNA cross-linking agent, Carboplatin.
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| DC46882 | Lomardexamfetamine |
Lomardexamfetamine (KP 106) is an orally active central nervous system stimulant composed of d-amphetamine and a ligand. Lomardexamfetamine can be used for the research of attention-deficit hyperactivity disorder.
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| DC46881 | Fosdenopterin |
Fosdenopterin (Precursor Z) is a synthetic cyclic pyranopterin monophosphate (cPMP). Fosdenopterin can be used for the research of molybdenum cofactor deficiency (MoCD) type A.
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| DC46879 | (S)-Coriolic acid |
(S)-Coriolic acid (13(S)-HODE), the product of 15-lipoxygenase (15-LOX) metabolism of linoleic acid, functions as the endogenous ligand to activate PPARγ. (S)-Coriolic acid is an important intracellular signal agent and is involved in cell proliferation and differentiation in various biological systems. (S)-Coriolic acid induces mitochondrial dysfunction and airway epithelial injury.
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| DC46878 | AMG131 |
AMG131 (INT131), a potent and highly selective PPARγ partial agonist, binds to PPARγ and displaces Rosiglitazone with a Ki of ~10 nM. AMG131 can be used for research of type-2 diabetes mellitus (T2DM).
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| DC46874 | Carbazeran citrate |
Carbazeran (citrate), a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran (citrate) can be used for the research of metabolic disease.
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| DC46873 | Senazodan hydrochloride |
Senazodan (MCI 154) (hydrochloride), as a Ca2+ sensitiser, shows inhibition effect on PDE III.
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| DC46869 | Luseogliflozin hydrate |
Luseogliflozin (TS 071) hydrate is a selective potent and orally active second-generation sodium-glucose co-transporter 2 (SGLT2) inhibitor with an IC50 of 2.26 nM. Luseogliflozin hydrate can be used for the research of type 2 diabetes mellitus (T2DM).
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| DC46867 | Ro 0437626 |
Ro 0437626 is a selective purinergic (P2X1) receptor antagonist (IC50 = 3 μM), but shows low affinity for P2X2, P2X3 and P2X2/3 receptors (IC50 > 100 μM).
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| DC46866 | NF110 |
NF110 is a P2X3 receptor antagonist (Ki = 36 nM) and inactive toward P2Y receptors stably expressed (IC50s > 10 M). NF110 blocks alphabeta-methylene-ATP-induced currents (IC50 = 527 nM) in rat dorsal root ganglia neurons.
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| DC46865 | α,β-Methylene-ATP dilithium |
α,β-Methylene ATP dilithium, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand. α,β-Methylene ATP dilithium is a highly selective agonist for P2X1 and P2X3, with practically no activity at P2X2,4-7.
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| DC46863 | Epiboxidine |
Epiboxidine is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. Epiboxidine is a methylisoxazole analog of the alkaloid Epibatidine, and is also an analog of another nAChR agonist, ABT 418.
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| DC46862 | D-AP4 |
D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid), a phosphono analogue of glutamate, is an NMDA broad spectrum excitatory amino acid receptor antagonist. D-AP4 also is an agonist for a quisqualate-sensitized AP6 site in hippocampus. D-AP4 inhibits AMPA receptor-stimulated 57Co2+ influx in cultured cerebellar granule cells (IC50 ≥ 100 μM).
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| DC46861 | Navocaftor |
Navocaftor, as a cystic fibrosis transmembrane regulator (CFTR), is a protein modulator (US 20200377491 Al, example 1).
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| DC46860 | Dirocaftor |
Dirocaftor (PTI-808) is a CFTR potentiator that enhances the function of CFTR protein by opening chloride channels. Dirocaftor can be used for cystic fibrosis (CF) research.
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| DC46859 | Bamocaftor |
Bamocaftor (VX-659) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore F508del-CFTR protein function. Bamocaftor can be used combine with Tezacaftor and Ivacaftor in cystic fibrosis research.
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| DC46858 | Norverapamil D7 hydrochloride |
Norverapamil D7 ((±)-Norverapamil D7) hydrochloride is a deuterium labeled Norverapamil. Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
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